Evidence map›Paper›PMID 42055555›Full record

ArticleDrug and alcohol review2026

At-Risk Substance Use Among Trans and Gender Diverse Adults in Australia: Findings From the Private Lives 3 Survey.

Emily Symes, Louisa Degenhardt, Natalie Amos, Adam Bourne, Adam O Hill, Ruth McNair, Marina Carman, Rachel Sutherland

Abstract read
In one paragraph

Article in Drug and alcohol review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emily SymesNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0000-0001-7928-4541
Louisa DegenhardtDrug Health Service, Royal Prince Alfred Hospital, Sydney, Australia.
Natalie AmosAustralian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, Australia.
Adam BourneAustralian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, Australia.
Adam O HillAustralian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, Australia.ORCID 0000-0001-5874-9821
Ruth McNairDepartment of General Practice and Primary Care, University of Melbourne, Melbourne, Australia.
Marina CarmanSafe and Equal, Melbourne, Australia.
Rachel SutherlandNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0000-0001-5337-1751

Funding

Australian Government Department of Health, Disability and AgeingVictorian Government Department of Health and Human ServicesVictorian Government Department of Premier and Cabinet
6 · The paper itself

Abstract

introductionTrans and gender diverse (trans) people face substantial health and social inequities, yet limited data exist regarding substance use patterns among this population in Australia.

methodsData were sourced from Private Lives 3, a large national survey of LGBTQ+ adults residing in Australia. Trans participants self-reported sociodemographic characteristics, experiences of discrimination, harassment, violence or exclusion, perceived acceptance and affirmation, psychological distress, sexual assault history and substance use behaviours. Multivariable regression analyses identified factors associated with potentially problematic illicit drug use (DAST-10 ≥ 3), potentially hazardous drinking (AUDIT-C ≥ 3), and daily smoking of cigarettes or other tobacco products.

resultsOf 1506 trans participants, 23.7% screened positive for potentially problematic illicit drug use, 49.8% for potentially hazardous alcohol use and 8.5% smoked daily. Potentially problematic illicit drug use was associated with unstable housing (aPR = 1.44, p = 0.001), psychological distress (aPR = 1.39, p = 0.022) and sexual assault history (aPR = 1.51, p = 0.001). Potentially hazardous alcohol use was less prevalent among those with affirming partners (aPR = 0.81, p = 0.001) and asexual identity (aPR = 0.65, p = 0.016), but more prevalent among those with a sexual assault history (aPR = 1.17, p = 0.012). Daily smoking was associated with unstable housing (aPR = 1.82, p = 0.002) and sexual assault history (aPR = 2.09, p = 0.002). DISCUSSION AND

conclusionsAt-risk substance use among Australian trans adults was most associated with sexual assault and unstable housing, but not gender identity, perceived acceptance, or most experiences of discrimination, harassment, violence, or exclusion. These findings differ from many US studies and may reflect regional sociocultural, legal or healthcare differences, or unmeasured determinants. These findings highlight the need for routine substance-use screening, trauma-informed care, and housing and sexual assault support initiatives for trans Australians.

Indexed as

Substance-Related DisordersTransgender PersonsAdolescentAdultAlcohol DrinkingAustraliaFemaleHumansMaleMiddle AgedRisk FactorsSmokingSurveys and QuestionnairesYoung AdultAustraliagender‐nonconforming personssexual assaultsubstance usetransgender persons

Identifiers

PMID42055555
PMCPMC13128307

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.