Evidence map›Paper›PMID 42054973›Full record

ReviewDevelopmental cognitive neuroscience2026

The interplay between executive function and learning disabilities: Developmental cognitive neuroscience perspectives on reading, math, and ADHD.

Tzipi Horowitz-Kraus, Paul T Cirino, Laurie E Cutting, Sarah S Hughes-Berheim, Eric D Wilkey, Marcia A Barnes, Keri S Rosch, Jessica A Church

Abstract readReview
In one paragraph

Review in Developmental cognitive neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tzipi Horowitz-KrausEducational Neuroimaging Group, Department of Education in Science and Technology, Department of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa, Israel; CNIR, Kennedy Krieger Institute, Baltimore, United States; Johns Hopkins University School of Medicine, Baltimore, United States. Electronic address: Tzipi.Kraus@technion.ac.il.
Paul T CirinoDepartment of Psychology, University of Houston, Houston, TX, United States.
Laurie E CuttingDepartment of Special Education, Vanderbilt University, Nashville, TN, United States; Department of Psychology and Human Development, Vanderbilt University, Nashville, TN, United States.
Sarah S Hughes-BerheimDepartment of Special Education, Vanderbilt University, Nashville, TN, United States.
Eric D WilkeyDepartment of Psychology and Human Development, Vanderbilt University, Nashville, TN, United States.
Marcia A BarnesDepartment of Special Education, Vanderbilt University, Nashville, TN, United States.
Keri S RoschCNIR, Kennedy Krieger Institute, Baltimore, United States; Johns Hopkins University School of Medicine, Baltimore, United States.
Jessica A ChurchDepartment of Psychology, University of Texas at Austin, Austin, TX, United States.

Funding

VALIDITY OF SUBTYPES OF ADHDP50HD027802 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI ERIK G WILLCUTT · 1990 to 2026
$44.9M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Texas Center for Learning DisabilitiesP50HD052117 · NICHD · UNIVERSITY OF HOUSTON · PI FLETCHER, JACK M · 2006 to 2023
$26.9M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Cognitive and Neural Processes in Reading ComprehensionR01HD044073 · NICHD · VANDERBILT UNIVERSITY · PI CUTTING, LAURIE E · 2004 to 2019
$8.1M
Early Academic Achievement and Intervention Response: Role of Executive FunctionR37HD095519 · NICHD · VANDERBILT UNIVERSITY · PI Laurie E Cutting · 2018 to 2026
$5.1M
Neural Correlates of Discourse Processing in AdolescentsR01HD109151 · NICHD · VANDERBILT UNIVERSITY · PI Laurie E Cutting · 2022 to 2026
$3.4M
Predicting Late-Emerging RD: Neurobiological and Cognitive FactorsR01HD067254 · NICHD · VANDERBILT UNIVERSITY · PI CUTTING, LAURIE E · 2010 to 2014
$2.9M
The role of executive functions in reading and reading remediationR01HD086011 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI HOROWITZ-KRAUS, TZIPI · 2016 to 2020
$2.5M
NCATS NIH HHS UL1 TR000445NICHD NIH HHS P50 HD027802NICHD NIH HHS P50 HD052117NICHD NIH HHS P50 HD103537NICHD NIH HHS R01 HD044073NICHD NIH HHS R01 HD067254NICHD NIH HHS R01 HD086011NICHD NIH HHS R01 HD109151NICHD NIH HHS R37 HD095519
6 · The paper itself

Abstract

The term "Executive function" (EF) describes domain-general cognitive processes including working memory, inhibitory control, and cognitive flexibility among others, that are essential for academic learning and behavioral regulation. Growing evidence highlights the importance of EF not only in typical development but also in understanding and intervening in learning disabilities (LDs), including dyslexia and dyscalculia, and in attention-deficit/hyperactivity disorder (ADHD). Despite this recognition, challenges remain in clearly defining EF, specifying its neurobiological underpinnings, and understanding its diverse roles across academic domains. This invited review reflects on a recent international expert workshop at the Flux Congress in 2024, and unites theoretical, behavioral, and neurobiological perspectives to examine how EF interacts with reading, math, and LDs. We explore the contribution of EF to word recognition, reading comprehension, and fluency; the role of audiovisual integration and cognitive control in dyslexia; the developmental interplay between EF and math difficulties; the role of EF in response to intervention in math; and EF as a transdiagnostic mechanism in ADHD and LD comorbidity. Across domains, we review the underlying brain networks, highlight methodological advances (e.g., functional connectivity, mobile neuroimaging), and discuss intervention strategies that target EF to support academic growth. We conclude with a synthesis of cross-cutting challenges and future directions, including the need for developmental models that integrate cognitive neuroscience, educational theory, and clinical insights. This review provides a roadmap for researchers and clinicians aiming to harness EF as a core mechanism to better understand and support diverse learners.

Indexed as

Attention Deficit Disorder with HyperactivityDyscalculiaDyslexiaExecutive FunctionLearning DisabilitiesReadingBrainCognitive NeuroscienceHumansMathematicsADHDAttention abilitiesDyscalculiaDyslexiaEEGExecutive functionsFluencyFMRILearningLearning difficultiesMathReading

Identifiers

PMID42054973
PMCPMC13141793

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.