Evidence map›Paper›PMID 42054811›Full record

ArticleInternational journal of hygiene and environmental health2026

Maternal residential proximity to oil and gas development in California and the risk of childhood cancer.

Yixin Chen, Lara J Cushing, Shiwen Li, Myles Cockburn, Zuo-Feng Zhang, Beate R Ritz, Julia E Heck

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of hygiene and environmental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yixin ChenDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA.
Lara J CushingDepartment of Environmental Health Sciences, University of California Los Angeles, Los Angeles, CA, USA.
Shiwen LiDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA.
Myles CockburnNorris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Zuo-Feng ZhangDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA.
Beate R RitzDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA; Department of Neurology, David Geffen School of Medicine, Los Angeles, CA, USA.
Julia E HeckDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA; College of Health and Public Service, University of North Texas, Denton, TX, USA. Electronic address: Julia.Heck@unt.edu.

Funding

UCLA CANCER EPIDEMIOLOGY TRAINING PROGRAMT32CA009142 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZUO-FENG · 1986 to 2024
$6.3M
Air Pollution and Childhood Cancers in CaliforniaR21ES018960 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HECK, JULIA · 2010 to 2011
$421k
Pesticide Exposure and Childhood Cancer StudyR21ES019986 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RITZ, BEATE R. · 2011 to 2012
$409k
NCI NIH HHS T32 CA009142NIEHS NIH HHS R21 ES018960NIEHS NIH HHS R21 ES019986
6 · The paper itself

Abstract

This study investigates maternal residential proximity to oil and gas development (OGD) in pregnancy and the risk of multiple childhood cancers in California. Cases (N = 9487) were identified from California Cancer Registry and controls (N = 183834) were randomly selected from the California Birth Registry (20:1 frequency-matched by birth year: 1998-2016), restricting both to births within 10 km of OGD. Exposure was defined as residing within 1 km or 3 km of any well at birth; 'low' and 'high' exposures were defined by the median well count within each distance. Unconditional logistic regression models estimated cancer risks comparing each exposed group to the unexposed (residing 3-10 km from any well). The risks of several cancers among children of mothers exposed to any well increased: medulloblastoma (within 3 km: adjusted Odds Ratio (aOR): 1.40; 95% confidence interval (CI): 1.08, 1.82; low, aOR = 1.27; 95% CI = 0.93, 1.74; high, aOR = 1.55; 95% CI = 1.14, 2.11); rhabdomyosarcoma (within 3 km: aOR = 1.64; 95% CI = 1.28, 2.09) with similar estimates across low and high exposure levels; and teratoma (within 3 km: aOR = 1.42; 95% CI = 0.99, 2.05; low, aOR = 1.35; 95% CI = 0.88, 2.07; high, aOR = 1.51; 95% CI = 0.98, 2.33). The results were consistent across both buffer sizes (1 km and 3 km) and estimates were similar for any well and inactive wells. No clear associations were observed for other major childhood cancers including leukemias and lymphomas. Our study suggests that OGD may increase the risk of developing several rare childhood cancers.

Indexed as

Maternal ExposureNeoplasmsOil and Gas IndustryPrenatal Exposure Delayed EffectsAdultCaliforniaCase-Control StudiesChildChild, PreschoolFemaleHumansInfantMalePregnancyRisk FactorsChildhood cancerOil and gas developmentPregnancy

Identifiers

PMID42054811
PMCPMC13283020

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.