Trial reportPloS one2026
Effects of hearing intervention on physical function: A secondary analysis of the ACHIEVE study.
Trial report in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03243422 (Aging and Cognitive Health Evaluation in Elders), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Aging and Cognitive Health Evaluation in Elders (ACHIEVE) Randomized Trial
Who cites it
1 citing paper in PubMed.
- Physical function impacts hearing without mediation from systolic blood pressure.Scientific reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe tested the effect of the hearing intervention vs. health education control (1:1 randomization) on 3-year physical function decline, a secondary analysis of the ACHIEVE randomized trial (ClinicalTrials.gov Identifier: NCT03243422).
methodsPre-specified outcomes included the Short Physical Performance Battery (SPPB) [total score and components] and grip strength. Intervention effects were modeled using linear mixed models following a pre-specified statistical analysis plan.
resultsIn 956 participants (mean 76.3 years, 53% female, 12% Black race), hearing intervention did not impact change in SPPB (difference comparing intervention to control = 0.00 standard deviation [SD] units, 95% confidence interval [CI]:-0.14, 0.14) or grip strength (difference = 0.01 SD, 95% CI: -0.06, 0.08). However, treatment effects varied by recruitment cohort; although findings were not statistically significant, they suggest a clinically meaningful benefit (slower decline) in participants with faster rates of cognitive decline.
conclusionsThese secondary results have direct relevance for inclusion in systematic reviews and meta-analyses. Future research should be designed to test whether hearing intervention can reduce short-term declines in physical function, particularly among those experiencing cognitive decline. Continuing follow-up of the ACHIEVE study participants will yield insights into longer-term (>3 years) effects of intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.