ArticleJournal of the American Chemical Society2026
Chemoenzymatic Synthesis with Plant Oxidases and Metabolic Engineering Enable Rapid Access to Rare Gibberellins.
Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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4 authors.
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Abstract
Gibberellins are structurally complex diterpenoid plant hormones with widespread agricultural applications. However, of the 136 known congeners found in nature, very few are easily accessible, preventing further research regarding their biological function. In biosynthesis, oxidases from plants generate the diverse oxidation patterns of natural gibberellins. Plant oxidases, in contrast to microbial oxidases, are very challenging to use for chemoenzymatic synthesis. Here, we develop a chemoenzymatic and metabolic engineering platform using plant oxidases that allows the production and full characterization of eight rare gibberellins as well as 16
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