Evidence map›Paper›PMID 42054214›Full record

ArticleSTAR protocols2026

Surgical protocol for precise and high-throughput viral injections in rhesus monkey brain.

Anne Claire Tangen, Peyton Harmon, Anya S Plotnikova, Arya Mohanty, Alexander C Cummins, Kenneth A Pelkey, Katherine Cameron, Camille Rood, Kathryn Ann Guerriero, Chris J McBain and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in STAR protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anne Claire TangenLaboratory of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA. Electronic address: atangen@andrew.cmu.edu.
Peyton HarmonLaboratory of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Anya S PlotnikovaLaboratory of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA; Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; Lipschultz Center for Cognitive Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Arya MohantyLaboratory of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA; School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Alexander C CumminsLaboratory of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Kenneth A PelkeyEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA.
Katherine CameronSection on Instrumentation, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Camille RoodSection on Instrumentation, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Kathryn Ann GuerrieroVeterinary Medicine and Resources Branch, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Chris J McBainEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA.
Mark A G EldridgeLaboratory of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA; Newcastle University, NE1 7RU Newcastle upon Tyne, UK.
Bruno B AverbeckLaboratory of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Reza AzadiLaboratory of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA. Electronic address: reza.azadi@nih.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral injections in nonhuman primates allow modification of neurons to investigate the organization and function of neural circuits, their developmental processes, and disease-related mechanisms. Here, we present a protocol for performing precise stereotaxic microinjections in the macaque brain. We describe steps for pre-surgical imaging, target planning, viral injections, and perioperative care. We then detail procedures for tissue extraction and slice electrophysiology experiments in multiple subcortical and cortical regions. For complete details on the use and execution of this protocol, please refer to Furlanis et al.

Indexed as

BrainMicroinjectionsStereotaxic TechniquesAnimalsMacaca mulattaNeuronsBehaviorCognitive NeuroscienceNeuroscience

Identifiers

PMID42054214
PMCPMC13136701

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.