Evidence map›Paper›PMID 42054168›Full record

ArticleEinstein (Sao Paulo, Brazil)2026

The use of an objective method (continuous exosomatic electrodermal activity without external stimuli) to evaluate patients with hyperhidrosis undergoing video-assisted sympathectomy.

Rafael José Silveira, Carolina Carvalho Jansen Sorbello, Nelson Wolosker, José Ribas Milanez de Campos, João José de Deus Cardoso, Alexandre Sherlley Casimiro Onofre

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Article in Einstein (Sao Paulo, Brazil), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Rafael José SilveiraDepartment of Clinical Surgery, Hospital Universitário, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.ORCID http://orcid.org/0000-0002-6985-7649
Carolina Carvalho Jansen SorbelloHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0004-1229-5130
Nelson WoloskerHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-1991-3507
José Ribas Milanez de CamposHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-2385-7707
João José de Deus CardosoDepartment of Clinical Surgery, Hospital Universitário, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Alexandre Sherlley Casimiro OnofreDepartment of Clinical Analysis, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.ORCID http://orcid.org/0000-0003-1883-6087

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze continuous exosomatic electrodermal activity (EDA) without external stimuli (EDAcw) in patients with primary hyperhidrosis before and after sympathectomy.

methodsThis prospective study included 28 participants, categorized into two groups. The first group comprised 18 patients with palmoplantar hyperhidrosis who underwent bilateral thoracic sympathectomy. The second group (control) consisted of 10 patients. Two questionnaires were administered: the Control Group completed them once, whereas the Sympathectomy Group completed them preoperatively, and on the first and thirtieth postoperative days. Sweating was evaluated by measuring EDAcw using an MP36R biosensor. Measurements were obtained from the hands and feet for 5 min without external stimuli in an air-conditioned environment and were performed preoperatively, and on the first and thirtieth postoperative days. Anthropometric, clinical, and surgical data were collected, and no significant sociodemographic differences were observed between the groups.

resultsIn the Sympathectomy Group, quality of life improved, and sweating reduced. During preoperative assessment, EDA was higher in the hands and feet of patients with hyperhidrosis than in the Control Group. Postoperatively, EDA in the hands decreased, with 100% of the patients showing a decrease in sweating. For the feet, 67% of the patients reported reduced sweating, and 44% showed a statistically significant decline in EDA.

conclusionContinuous exosomatic EDA measurement without external stimuli is a suitable method for assessing patients with palmoplantar hyperhidrosis and shows appropriate clinical correlation.

Indexed as

Galvanic Skin ResponseHyperhidrosisSympathectomyThoracic Surgery, Video-AssistedAdolescentAdultCase-Control StudiesFemaleHandHumansMaleMiddle AgedPostoperative PeriodProspective StudiesQuality of LifeSurveys and Questionnaires

Identifiers

PMID42054168
PMCPMC13128233

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