Observational studyDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2026
Peristalsis of the gastric conduit post-esophagectomy: is it relevant? Detailed conduit analysis using dynamic magnetic resonance imaging.
Observational study in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of esophageal cancer resections is rising, and survivorship improving. Consequently, more patients are living longer with gastric conduits and enduring the associated morbidity. Gastric conduit shape and peristalsis are believed to mediate conduit function, gastrointestinal symptoms, and quality of life (QoL). However, the relationship between anatomical variations, peristaltic function, and conduit emptying remains largely undefined. This prospective observational study recruited patients with gastric conduits at least 2 years post-esophagectomy and controls with normal gastric anatomy. Dynamic and static MRI sequences were obtained following porridge ingestion. Nuclear scintigraphy conduit emptying studies were available for 17 out of 18 (94%) patients. QoL questionnaire data were collected. Eighteen patients with conduits and 12 controls were recruited. Peristalsis was measurable in 15 conduits. There was no difference in peristaltic wave frequency between conduits and controls (5 waves per 90 seconds in each group) or median Gastric Motility Index Interquartile Range (IQR) 35.45 mm2/second (17.3-47.5) vs 36.5 mm2/second (9.8-99.4) p = 0.61. Gastric emptying was significantly reduced in conduit patients (0.10% vs 15% p = 0.01). Acute angulation and conduits wider than 4 cm were associated with slower emptying (444 minutes vs 127 minutes, p = 0.025) and (286 minutes vs 76 minutes, p = 0.02), respectively. Delayed emptying demonstrated a significant positive correlation with reflux (rs0.614, p = 0.009) and increased gastrointestinal symptoms (rs0.553, p = 0.021). Peristalsis is present in most conduits, but it does not correlate with improved emptying. Anatomical features, particularly conduit angulation and width influence conduit function. These findings may guide further research into optimizing conduit formation and treating dysfunction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.