Evidence map›Paper›PMID 42053948›Full record

ArticleJournal of robotic surgery2026

Mako robot-assisted total knee arthroplasty mitigates the impact of surgeon handedness.

Minjiao Wu, Jiayan Chen, Yaping Wang, Lingjun Jiang, Shujun Chen, Chenglong Wang

Abstract read
In one paragraph

Article in Journal of robotic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Minjiao Wu *Department of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, 318000, Zhejiang, P.R. China.
Jiayan Chen *Department of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, 318000, Zhejiang, P.R. China.
Yaping Wang *Department of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, 318000, Zhejiang, P.R. China.
Lingjun JiangDepartment of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, 318000, Zhejiang, P.R. China. 1120@enzemed.com.
Shujun ChenDepartment of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, 318000, Zhejiang, P.R. China. chensj@enzemed.com.
Chenglong WangDepartment of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, 318000, Zhejiang, P.R. China. wangcl4779@enzemed.com.

Funding

Taizhou Science and Technology Plan 25ywb62Zhejiang Science and Technology Plan for Disease Prevention and Control 2026JKY312Zhejiang Science and Technology Plan for Health Commission 2025HY1427
6 · The paper itself

Abstract

Surgeon handedness may influence prosthetic alignment in conventional manual total knee arthroplasty (CM-TKA), but whether robotic assistance mitigates this effect remains unclear. This study investigated whether Mako robot-assisted TKA (MA-TKA) mitigates handedness-related discrepancies in alignment accuracy and perioperative outcomes. This retrospective cohort study included 1160 patients who underwent unilateral TKA performed by three experienced right-handed surgeons. Patients were divided into four groups based on surgical technique and operated side: MA-left (n = 84), MA-right (n = 92), CM-left (n = 453), and CM-right (n = 531). Operative duration, tourniquet time, hospital stay, blood loss, and radiographic parameters (mechanical tibiofemoral angle, mechanical lateral distal femoral angle, medial proximal tibial angle, lateral femoral component and lateral tibial component) were compared. Outliers were defined as ≥ 3° deviation from target values. Baseline characteristics were comparable across groups. MA-left surgery had the longest operative and tourniquet times, while MA-right surgery yielded the lowest blood loss. Both MA groups had significantly shorter hospital stays and lower blood loss than CM groups (P < 0.001). Radiographic accuracy was superior in MA groups, with no differences between MA-left and MA-right for any parameter. In CM groups, left-sided procedures showed significantly poorer alignment and higher outlier rates than right-sided procedures (P < 0.05). MA-TKA mitigates the negative impact of surgeon handedness on prosthetic alignment, achieving homogeneous accuracy regardless of operated side. Despite slightly longer operative times, MA-TKA reduces blood loss and shortens hospital stay, offering tangible clinical value.

Indexed as

Arthroplasty, Replacement, KneeFunctional LateralityRobotic Surgical ProceduresSurgeonsAgedBlood Loss, SurgicalFemaleHumansLength of StayMaleMiddle AgedOperative TimeRetrospective StudiesClinical outcomesComponent alignmentHandednessMako robotic-assistedTotal knee arthroplasty

Identifiers

PMID42053948
PMCPMC13128775

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.