ArticleArchives of gynecology and obstetrics2026
Benefits of minimal ethanol volume and retention without removal in transvaginal ethanol sclerotherapy for endometriomas.
Article in Archives of gynecology and obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThis study aims to introduce an effective protocol for transvaginal ethanol sclerotherapy, focussing on the aspiration of viscous cystic content and the amount of ethanol instilled in the cystic cavity according to cyst size.
methodsWe retrospectively reviewed the medical records of 90 women who underwent transvaginal ethanol sclerotherapy from 2015 to 2022 at Good Moonhwa Hospital, Busan, Republic of Korea. The volume of ethanol used for sclerotherapy was determined based on the initial volume of aspirated cystic content, with a target limit of 30 cc, and the injected alcohol was retained within the cystic cavity. All patients were followed up on postoperative days 1 and 2, at 2 weeks, 4 weeks, 3 months, 6 months, 12 months, and every 6 months thereafter to assess the ovary, AMH level, complications, recurrence, and pregnancy outcome.
resultsThe cyst size was 5.07 ± 1.56 cm. AMH levels increased in 22 cases (27.4%) and decreased in 68 cases (75.6%). Among the 68 cases that decreased, 38 cases (55.9%) showed a mild decrease of less than 30%. The change rates in AMH levels did not significantly correlate with cyst size, aspirated cyst volume, alcohol instillation volume, operation time, recurrence rate, or pregnancy outcome. The volume of alcohol instilled significantly correlated with operation time. Of the 44 patients (78.9%) who wished to conceive, 17 (38.6%) became pregnant (12 spontaneously and 5 via IVF-ET). Recurrence occurred in 6 cases (6.67%).
conclusionThis study demonstrates that our protocol for ethanol sclerotherapy not only significantly reduces the recurrence rate but also preserves ovarian reserve, as reflected by the minimal impact on AMH.
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