Evidence map›Paper›PMID 42053787›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Posterior spinal fusion for Lenke 1 C and 2 C AIS: can the lowest instrumented vertebra stop at the lumbar apex?

Jie Chen, Zhong He, Yi Chen, Xiaodong Qin, Zhen Liu, Minxuan Sun, Dong Xie, Hifza Babar, Yankun Jiang, Yong Qiu and 1 more

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Jie ChenThe Affiliated Chuzhou Hospital of Anhui Medical University, The First Peoples Hospital of Chuzhou, Anhui Hui, China.
Zhong HeNanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Yi ChenNanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Xiaodong QinNanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Zhen LiuNanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Minxuan SunNanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Dong XieNanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Hifza BabarNanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Yankun JiangNanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Yong QiuNanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Zezhang ZhuThe Affiliated Chuzhou Hospital of Anhui Medical University, The First Peoples Hospital of Chuzhou, Anhui Hui, China. zhuzezhang@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify risk factors for distal adding-on (AO) in Lenke 1 C/2 C AIS patients with the lowest instrumented vertebra (LIV) at the lumbar apex vertebra (LAV).

methodsThis study included 60 Lenke 1 C/2 C AIS patients undergoing posterior spinal fusion with LIV at LAV and > 2 years follow-up. Patients were categorized into AO (n = 17) and non-AO (n = 43) groups. Radiographic analysis assessed thoracic/lumbar curve flexibility, apical vertebral translation (AVT), LAV rotation/tilt, coronal balance, Harrington stable zone on anteroposterior(AP)and concave-side bending films, and LAV/AV + 1 disc opening/closing status. Clinical outcomes used SRS-22. Statistical comparison was performed.

resultsThe AO group exhibited significantly poorer preoperative thoracic curve flexibility, greater coronal imbalance toward the lumbar convex side, larger lumbar AVT, smaller Harrington stable zones, and fewer patients with favorable LAV/AV + 1 disc status. Logistic regression identified thoracic flexibility, Harrington stable zone on concave-side bending, and disc status as significant AO predictors. Optimal thresholds for selecting LAV as LIV were thoracic flexibility > 47.4% ,concave-side bending Harrington zone > 84.9% ,and favorable opening/closing status of the LAV/AV + 1 disc .At final follow-up, the AO group had larger lumbar Cobb angle and AVT with lower correction rates, but SRS-22 scores showed no significant difference.

conclusionFor Lenke 1 C/2 C AIS, terminating LIV at LAV is feasible when thoracic flexibility is good (> 47.4%), the LAV/AV + 1 disc status is favorable, and the Harrington stable zone on concave-side bending is large (> 84.9%).

Indexed as

Adding-on phenomenonAdolescent idiopathic scoliosisLenke 1 CLenke 2 CLowest instrumented vertebraLumbar apex vertebra

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.