ReviewDiscover oncology2026
Functions and mechanisms of exosomal lncRNAs in esophageal cancer.
Review in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Esophageal cancer is a prevalent and highly aggressive malignancy with poor clinical outcomes, largely due to late diagnosis and limited effective biomarkers. Improved understanding of its molecular mechanisms and the identification of reliable non-invasive diagnostic indicators are therefore of critical importance. Exosomes are small double-membrane extracellular vesicles present in various biological fluids that mediate intercellular communication through the transfer of bioactive cargo, including proteins and RNAs. Among these cargos, long non-coding RNAs (lncRNAs) packaged within exosomes have emerged as key regulators of tumor initiation, progression, metastasis, and therapeutic resistance. Increasing evidence indicates that exosomal lncRNAs play crucial roles in esophageal cancer by modulating cell proliferation, migration, invasiveness, angiogenesis, and response to treatment, while also exhibiting high stability in circulation, making them promising diagnostic and prognostic biomarkers. This review summarizes recent advances in the biological functions, clinical relevance, and translational potential of exosomal lncRNAs in esophageal cancer, highlighting their emerging value in liquid biopsy and targeted therapeutic strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.