ArticleIndian pediatrics2026
Efficacy of 800 IU Versus 400 IU Daily Oral Vitamin D
Article in Indian pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo determine the efficacy and safety of daily supplementation of 800 IU versus 400 IU vitamin D
methodsAn open-label randomized controlled trial including exclusively breastfed term SGA infants was conducted in a tertiary care hospital. Eligible infants were randomized within 24 h of life to receive either 800 IU or 400 IU daily oral vitamin D
resultsAmong 60 enrolled infants, the distribution of baseline variables was similar in both groups. The proportion of infants with VDI at 14 weeks was significantly less in 800 IU (30%) versus 400 IU (63.3%) group (RR = 0.47, 95% CI 0.18, 0.73; P = 0.016). In the 800 IU group, there was a trend towards reduction in the proportion of infants with VDD, and no infant with severe VDD. Clinical rickets was seen in 3 infants (1 in 800 IU and 2 in 400 IU), with all having VDD. None of the infants had VDT.
conclusionDaily oral supplementation of 800 IU vitamin D
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