ReviewStem cell reviews and reports2026
The Evolution of Organoids: From Discovery to Cutting-Edge Applications.
Review in Stem cell reviews and reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The in vitro organoid concept is a significant technical advancement that has proven to be a valuable tool in a variety of fundamental biology and therapeutic applications. This physiologically relevant 3D model enables the study of key in vivo biochemical processes such as tissue regeneration, stem cell/niche activities, and tissue response to medicines, mutations and injury. Organoids bridge conventional 2D cultures, in vivo human and murine systems because they provide greater physiological relevance than monolayer models while remaining more experimentally accessible than animal models. This innovative platform and its multiorgan incorporation, which recapitulates organ-level function and structure, enables a wide range of applications such as human disease models, which may help reduce reliance on animal testing. This review explores the concepts of organoids and organ-on-a-chip as well as current advances that lead to the development of in vitro disease models and novel therapeutic options.
Indexed as
Identifiers
42053724What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.