Evidence map›Paper›PMID 42053617›Full record

ReviewInnere Medizin (Heidelberg, Germany)2026

[Artificial intelligence-assisted diagnostics in the pathology of internal and oncological diseases].

Vincenzo Mitchell Barroso, Alexander Quaas, Reinhard Büttner, Yuri Tolkach

Abstract readEnglish AbstractReview
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In one paragraph

Review in Innere Medizin (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vincenzo Mitchell BarrosoInstitut für Pathologie, Universitätsklinikum Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Alexander QuaasInstitut für Pathologie, Universitätsklinikum Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Reinhard BüttnerInstitut für Pathologie, Universitätsklinikum Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Yuri TolkachInstitut für Pathologie, Universitätsklinikum Köln, Kerpener Str. 62, 50937, Köln, Deutschland. yuri.tolkach@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) is increasingly being implemented in digital pathology to support the tissue classification, cell detection, biomarker quantification, the grading and prediction of clinically relevant molecular alterations.

objectiveCurrent applications of AI in the pathology of internal and oncological diseases are summarized with a focus on the most important algorithm approaches, representative cases of diagnostic applications and current limits of clinical implementation. MATERIAL AND

methodsThis narrative overview of the most recent advances describes the essential model forms, including tissue segmentation systems, algorithms for recognition of individual cells, unsupervised learning and foundation models, tools for the evaluation of immunohistochemistry and multimodal or language-based applications. Representative studies on renal, liver, pulmonary, gastrointestinal, hematological and thyroid gland pathologies are discussed.

resultsIn many situations AI improves the reproducibility, objectiveness and efficiency. Some systems achieve an accuracy that is comparable to that of experts. Most AI tools are still in the validation stage and only a few have been transferred to routine clinical use. DISCUSSION: Artificial intelligence could further optimize the diagnostic and predictive histopathology. Their role remains assistive. A broad implementation is limited due to various hurdles and bottlenecks. The future progress depends on prospective validation and the integration into routine digital workflows.

Indexed as

Artificial IntelligenceDiagnosis, Computer-AssistedNeoplasmsAlgorithmsHumansReproducibility of ResultsAlgorithmsEfficiencyHistopathologyObjectivityReliability and validity

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.