Evidence map›Paper›PMID 42053582›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2026

Characterization of stable grain protein content loci on chromosome 6D without adverse effect on yield traits in bread wheat.

Hang Liu, Chao Wang, Jiating Chen, Huaping Tang, Tongzhu Wang, Md Nahibuzzaman Lohani, Hafiz Muhammad Faisal Umer, Muhammad Junaid Jalil, Haopeng Zhang, Xia Yang and 4 more

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Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Hang Liu *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Chao Wang *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Jiating Chen *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Huaping TangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Tongzhu WangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Md Nahibuzzaman LohaniState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Hafiz Muhammad Faisal UmerState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Muhammad Junaid JalilState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Haopeng ZhangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Xia YangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Qiang XuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Jian MaState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China/Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China. jianma@sicau.edu.cn.
Guangdeng ChenCollege of Resources, Sichuan Agricultural University, Chengdu, Sichuan, China. gdchen@sicau.edu.cn.
Meijin YeCollege of Chemistry and Life Sciences, Chengdu Normal University, Chengdu, 611130, China. 091048@cdnu.edu.cn.

Funding

National Key R&D Program of China 2023YFD1201900
6 · The paper itself

Abstract

key messageThis study identified and validated novel QTL controlling GPC, predicted the underlying candidate genes, and provides valuable insights for improving wheat nutritional quality while minimizing yield penalties. Grain protein content (GPC) is a key determinant of wheat quality, but its improvement is often limited by a negative correlation with yield. To elucidate the genetic architecture of GPC, a genome-wide association study was conducted on 224 wheat cultivars genotyped with a 120 K SNP array and phenotyped across three environments. We identified three stable quantitative trait loci (QTL) on chromosome 6D, QGPC.sau-SCV-6D.1, QGPC.sau-SCV-6D.2, and QGPC.sau-SCV-6D.3 which were consistently detected across environments and in best linear unbiased prediction analyses. These loci explained 4.94-9.12% of the phenotypic variance. Notably, the GPC increasing alleles exhibited no adverse effect on major yield components, including thousand-grain weight and grain number per spike. Validation in two independent recombinant inbred line populations confirmed the stable effects of these three QTL. Candidate gene analysis within the QTL intervals highlighted five genes with putative roles in regulating GPC. These findings establish chromosome 6D as a valuable genomic region for breeding high-protein wheat and provide practical markers for marker-assisted selection with minimal yield penalties.

Indexed as

Chromosomes, PlantGrain ProteinsQuantitative Trait LociTriticumAllelesChromosome MappingEdible GrainGenome-Wide Association StudyGenotypePhenotypePolymorphism, Single NucleotideSeedsGrain Proteins

Identifiers

PMID42053582

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.