Evidence map›Paper›PMID 42053469›Full record

SynthesisBJS open2025

Differences in recovery time between trapeziectomy and carpometacarpal joint replacement: meta-analysis.

Lauren Y Chong, Olivia J Hartrick, Chetan Khatri, Ciaran Sandhu, Sumedh Bele, Jeremy Rodrigues, Conrad Harrison

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BJS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lauren Y ChongSchool of Medicine and Biomedical Sciences, University of Oxford, Oxford, UK.ORCID 0009-0000-9572-1561
Olivia J HartrickHealthcare Management Leadership Innovation, Oxford University Hospitals NHS Trust, Oxford, UK.
Chetan KhatriClinical Trials Unit, University of Warwick, Coventry, UK.
Ciaran SandhuSchool of Medicine and Biomedical Sciences, University of Oxford, Oxford, UK.
Sumedh BeleNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Jeremy RodriguesClinical Trials Unit, University of Warwick, Coventry, UK.
Conrad HarrisonNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThumb-base osteoarthritis is a common degenerative condition that produces symptoms including pain and reduced hand function. Trapeziectomy is the mainstay surgical intervention following failure of conservative management and steroid injection, with carpometacarpal (CMC) joint replacement anticipating faster recovery time and return to work. However, there is limited evidence on recovery following both surgeries, which affects patient counselling and future research design.

methodsA preregistered (CRD42023450865) systematic review of the literature was conducted according to the PRISMA guidelines. Disability of the Arm, Shoulder and Hand (DASH) questionnaire scores, grip strength, and key pinch strength scores were obtained at different timepoints during follow-up. Standardized mean changes (SMC) were calculated and pooled through random-effects meta-analysis before being plotted at monthly timepoints.

resultsOf 63 articles eligible for inclusion, 25 studies were included in the meta-analysis. Subgroup analyses were conducted comparing types of trapeziectomy, joint replacement implants, and immobilization protocols. At the 1-month follow-up, joint replacement was associated with a trend of improvement in the DASH score, whereas trapeziectomy was associated with a deterioration. At 12 months, joint replacement showed a trend of greater improvement in hand function than trapeziectomy. Key pinch strength returned to baseline function at 1.5 months after joint replacement, compared with 6 months after trapeziectomy. Newer dual-mobility implants were associated with a quicker trend of recovery in DASH and key pinch strength than single-mobility implants. However, confidence intervals overlapped considerably, and most study arms had a high risk of bias, so these findings should not be considered statistically significant.

conclusionThis study shows a trend towards faster early recovery after CMC joint replacement compared with trapeziectomy, although the evidence remains limited. Randomized clinical trials with systems to frequently capture patient-reported outcomes data are required to study the temporal course of recovery for both surgeries.

Indexed as

Arthroplasty, ReplacementCarpometacarpal JointsOsteoarthritisRecovery of FunctionTrapezium BoneDisability EvaluationHand StrengthHumansPinch StrengthReturn to WorkThumbTime FactorsTreatment Outcomehand functionpost-operative recoverythumb-base osteoarthritis

Identifiers

PMID42053469
PMCPMC13126664

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.