Evidence map›Paper›PMID 42053231›Full record

ArticlePsycho-oncology2026

The Role of Metacognition, Intolerance of Uncertainty, and Cognitive-Attentional Syndrome in Differentiating Fear of Cancer Recurrence.

Wendy W T Lam, Danielle W L Ng, Ceci Guo, Rachel Ng, Richard Fielding, Chi Chung Foo, Ava Kwong, Siu-Man Simon Ng, Dacita Suen, Sara Fung and 4 more

Abstract read
In one paragraph

Article in Psycho-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Wendy W T LamDivision of Behavioural Sciences, Centre for Psycho-Oncological Research and Training, School of Public Health, The University of Hong Kong, Hong Kong, Hong Kong.
Danielle W L NgDivision of Behavioural Sciences, Centre for Psycho-Oncological Research and Training, School of Public Health, The University of Hong Kong, Hong Kong, Hong Kong.ORCID https://orcid.org/0000-0003-4919-0610
Ceci GuoDivision of Behavioural Sciences, Centre for Psycho-Oncological Research and Training, School of Public Health, The University of Hong Kong, Hong Kong, Hong Kong.
Rachel NgDivision of Behavioural Sciences, Centre for Psycho-Oncological Research and Training, School of Public Health, The University of Hong Kong, Hong Kong, Hong Kong.
Richard FieldingDivision of Behavioural Sciences, Centre for Psycho-Oncological Research and Training, School of Public Health, The University of Hong Kong, Hong Kong, Hong Kong.
Chi Chung FooDepartment of Surgery, The University of Hong Kong, Hong Kong, Hong Kong.
Ava KwongDepartment of Surgery, The University of Hong Kong, Hong Kong, Hong Kong.
Siu-Man Simon NgDepartment of Surgery, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID https://orcid.org/0000-0002-5389-9297
Dacita SuenDepartment of Surgery, The University of Hong Kong, Hong Kong, Hong Kong.
Sara FungDepartment of Surgery, Kwong Wah Hospital, Hong Kong Hospital Authority, Hong Kong, Hong Kong.ORCID https://orcid.org/0000-0002-2885-3369
Oi Kwan ChunDepartment of Surgery, Kwong Wah Hospital, Hong Kong Hospital Authority, Hong Kong, Hong Kong.
Karen K L ChanDepartment of Obstetric and Gynaecology, The University of Hong Kong, Hong Kong, Hong Kong.
Wendy W L ChanDepartment of Clinical Oncology, The University of Hong Kong, Hong Kong, Hong Kong.
Amy T Y ChangComprehensive Oncology Centre, Hong Kong Sanatorium & Hospital, Hong Kong, Hong Kong.

Funding

General Research Fund of the Research Grants Council of Hong Kong 17613221General Research Fund of the Research Grants Council of Hong Kong 17616619
6 · The paper itself

Abstract

objectivesThis study tested (1) whether intolerance of uncertainty (IU) and negative metacognitive beliefs independently differentiate fear of cancer recurrence (FCR) status, and (2) whether mediation by cognitive-attentional syndrome (CAS) elements modify the relationships of IU and metacognitive beliefs with FCR status.

methodsBaseline data from 384 participants (collected ∼15.6 months post-diagnosis) pooled from a prospective longitudinal study and an FCR intervention trial were analyzed. Measures included FCRI-SF (FCR), MCQ-30 (metacognitive beliefs), IUS-12 (IU), and CAS-1 (CAS). FCR status was classified based on the FCRI-SF scores as non-clinical (< 13), subclinical (13-21), and clinically significant (≥ 22). Fully adjusted multinomial logistic regression examined direct effects of IU and metacognitive domains on FCR status and indirect effects via CAS.

resultsCompared to the non-clinical group (n = 116), subclinical (n = 190) and clinically-significant (n = 78) FCR groups showed greater negative beliefs about worry (OR range 1.297-1.500, p < 0.001), higher IU (OR 1.050-1.066, p = 0.037), increased use of CAS metacognitive strategies (OR 1.077-1.108, p = 0.021-< 0.001), and less perceived need to control thoughts (OR 0.847-0.857, p = 0.003-0.027). Clinically-significant FCR was additionally associated with poorer cognitive confidence (OR 1.122, p = 0.030). CAS partially mediated associations of FCR status with negative beliefs about worry, cognitive confidence, and IU, and fully mediated the association with need to control thoughts.

conclusionsIU and negative metacognitive beliefs can characterize individuals vulnerable to differentially-elevated FCR. CAS centrally mediates the relationships between FCR, IU, and metacognition. Cognitive-behavioral interventions for FCR explicitly targeting CAS should disrupt the impact of IU and metacognitive beliefs on FCR.

Indexed as

AttentionCognitionFearMetacognitionNeoplasm Recurrence, LocalNeoplasmsAdultAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesUncertaintycancer survivorshipcognitive‐attentional syndromefear of cancer recurrenceintolerance of uncertaintymetacognition

Identifiers

PMID42053231
PMCPMC13127241

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.