ReviewActa paediatrica (Oslo, Norway : 1992)2026
Review Showed That Better Screening Is Still Needed for a Minority of Severe and Critical Congenital Heart Defects.
Review in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe review explored the effectiveness of different screening strategies for detecting severe and critical congenital heart defects (CHDs) before neonates were discharged from hospital after birth. These were prenatal fetal ultrasounds, postnatal pulse oximetry (POX), and clinical examinations.
methodsThis paper references studies that were published from 2005 to 2025, with a particular emphasis on those from Nordic countries.
resultsPrenatal detection rates of 42%-46% in live born infants were registered in nationwide studies. Pregnancy termination rates for severe or critical CHDs increased to 25%-43% and these influenced the prevalences and postnatal detection patterns of such defects. When CHDs that were detected prenatally were excluded, POX screening on the first day of life detected 11%-47% of severe and critical CHDs, depending on the inclusion criteria. When those detected by POX screening were excluded, routine clinical examinations identified 39%-58% of the cases in apparently healthy infants. The remainder were detected because of symptoms or some comorbidity. In infants born in 2014-20, 85%-89% of the severe and critical CHDs were found before discharge.
conclusionAlthough most severe and critical CHDs were detected before discharge, there are still challenges with regard to developing better screening methods to reduce cases that have been missed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.