ArticleJournal of the American Heart Association2026
Methamphetamine Use Among Adult Patients Presenting With Acute Coronary Syndrome: A Single-Center Retrospective Cohort Study.
Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
backgroundMethamphetamine-associated acute coronary syndrome (ACS) has not been previously well studied.
methodsThis retrospective, single-center study included all patients aged 18 to 65 years who presented with ACS and underwent coronary angiography from 2012 to 2022. Patients who used cocaine or had other non-type 1 myocardial infarction were excluded. Cox proportional hazard regression and survival analyses were performed to assess all-cause mortality.
resultsOne hundred ninety-four patients with methamphetamine-associated ACS were identified from 1309 ACS cases, for a prevalence of 14.8%. When compared with the 1115 patients with ACS without methamphetamine use, patients with methamphetamine-associated ACS were mostly younger men with a median age of 52 years (Q1-Q3: 47-57) versus 57 years (Q1-Q3: 51-61,
conclusionsACS related to methamphetamine use is primarily observed in younger men with adverse social determinants of health and is strongly associated with mortality. Strategies for prevention unique to this population are warranted.
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