SynthesisFrontiers in psychiatry2026
Adverse childhood experiences and the risk of non-suicidal self-injury: a meta-analysis.
Synthesis in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Systematically evaluate the association between Adverse Childhood Experiences (ACEs) and the risk of Non-suicidal Self-Injury (NSSI), thereby providing evidence-based guidance for relevant prevention and early intervention strategies. Methods: A systematic search was conducted across PubMed, Embase, Web of Science, and the Cochrane Library, from their inception to 30 November 2025, to identify observational studies reporting associations between ACEs and NSSI. Two researchers independently performed literature screening, data extraction, and quality assessment. Effect sizes were pooled using a random-effects model, with association strength expressed as odds ratios (OR) and their 95% confidence intervals (CI). Data analysis was conducted using Stata 15. Results: A total of 13 articles included. The meta-analysis results suggest that physical abuse [OR = 2.38, 95% CI (1.36, 4.16), I Conclusion: In summary, the findings of this meta-analysis suggest that exposure to adverse childhood experiences may be related to an increased likelihood of non-suicidal self-injury. Different forms of childhood adversity, including physical abuse, sexual abuse, and emotional abuse, as well as cumulative exposure to multiple ACEs, were associated with higher risks of NSSI. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42026128495.
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