ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2026
Unraveling Biofilm-Forming Uropathogens: Isolation and Antimicrobial Resistance Patterns at Nepal Police Hospital, Kathmandu.
Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Unraveling Biofilm-Forming Uropathogens: Isolation and Antimicrobial Resistance Patterns at Nepal Police Hospital, Kathmandu.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026Article
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7 authors.
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Abstract
Background: Urinary Tract Infections (UTIs) are common bacterial infections with growing treatment challenges due to the rise of antimicrobial resistance. Additionally, the characteristics of the pathogens responsible for UTIs are changing, primarily due to the emergence of biofilms. Biofilms, which are structured microbial communities, pose a significant public health threat because of their inherent resistance to antimicrobial treatments. Hence, this cross-sectional study aimed to isolate and characterize uropathogenic bacteria capable of forming biofilm and exhibiting antimicrobial resistance among patients seeking microbiology laboratory services at the Nepal Police Hospital. Methods: Uropathogens were isolated from midstream urine samples using CLED, Blood, and MacConkey agar. Standard microbiological techniques were employed for identification of pathogen. Antimicrobial susceptibility testing was conducted using the Kirby-Bauer disc diffusion method, and biofilm formation was assessed using the microtiter plate method. Results: Of the 2081 samples analyzed, significant bacterial growth was observed in 184 (8.84%) of the samples. The predominant pathogens were Conclusion: Biofilm-forming uropathogens present substantial challenges in UTI treatment. Importantly, our study did not find a correlation between antibiotic resistance and biofilm production, suggesting that these traits may be independent or influenced by different pathogenic mechanisms.
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