ArticleFrontiers in oncology2026
Triple-negative breast cancer, pregnancy, and HLA alloreactivity: a cause for concern?
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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2 authors.
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Abstract
Triple-negative breast cancer (TNBC) remains the most aggressive form of breast cancer in women worldwide, with an incidence that varies considerably depending on genetic background and ethnicity. Since parity is a known risk for TNBC, here we propose that in HLA alloreactivity resulting from immunization against paternal antigens expressed by the fetus, 50% fetus-mother HLA dissimilarity in natural pregnancy and 100% fetus-mother HLA dissimilarity in surrogate motherhood, may be a risk factor in women with predisposing genetic background and ethnicity due to immune suppression and immunologic tolerance vis-à-vis a developing breast cancer with TNBC characteristics.
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