ArticleSmall science2026
Cell-Size Confinement Drives Size-Dependent Scaling of Intracellular Reaction-Diffusion Waves for Robust Patterning.
Article in Small science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intracellular reaction-diffusion (iRD) waves are a mechanism to set the positions of molecules within cells for their proper biological function. Despite their biological importance, the physical characteristics of iRD waves were still elusive due to the specific constraints of cells, where spatial confinement and surface-bulk coupling govern pattern formation. Here, by an artificial cell experiment of iRD wave for cell division (Min wave) using defined factors, we showed that the wavelength of iRD wave is selected by the space size. This wavelength selection adjusted the wave shape and speed to fit the spatial sizes. Furthermore, this mechanism conferred the robustness of the macroscopic pattern of iRD waves under physicochemical perturbations. Theoretical analysis confirmed that this can be explained by the theoretical Min wave model and suggests its generality among iRD waves. These findings indicate the reason why cells use RD waves to place molecules with versatile functions.
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