ArticleFrontiers in microbiology2026
Distinct effects of a dairy probiotic drink and physical exercise on gut microbiota in pediatric acute lymphoblastic leukemia patients in remission: a randomized clinical trial.
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Integrative exercise and nutrition strategies in leukemia survivorship: implications for cognitive function and quality of life.Cancer cell international · 2026Review
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Authors and funding
10 authors.
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Abstract
Introduction: Treatment of pediatric acute lymphoblastic leukemia (ALL) induces persistent gut microbiota dysbiosis. However, microbiota-targeted interventions remain limited. This study evaluated the independent effects of physical exercise and probiotic supplementation on gut microbiota composition in pediatric ALL patients in remission for <5 years. Methods: Thirty patients were randomized to an experimental group (8-week exercise followed by 8-week daily probiotic intake) or a non-intervention control group. Gut microbiota composition, stool metabolite profiles, anthropometric parameters, and physical strength outcomes were assessed. Results: Physical exercise improved handgrip strength and supported anthropometric stability, with only modest effects on gut microbiota composition. In contrast, probiotic supplementation induced a significant shift in gut microbial community structure permutational multivariate analysis of variance (PERMANOVA, Discussion: Overall, probiotic supplementation had a greater impact on gut microbiota composition than physical activity, inducing targeted shifts toward a more favorable microbial profile in this clinically vulnerable population.
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