Evidence map›Paper›PMID 42052384›Full record

ArticleFrontiers in microbiology2026

Genomics, transcriptomics, and laboratory experiments link bioconvection to nitrogen fixation.

Francesco Di Nezio, Juan Diaz-Miyar, Antoine Buetti-Dinh, Samuele Roman, Tommaso Fava, Daniele Paganini, Nicola Storelli

Abstract read
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In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francesco Di Nezio *Anoxic Aquatic Systems Group, Institute of Microbiology, Department of Environment, Constructions and Design, University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Mendrisio, Switzerland.
Juan Diaz-Miyar *Anoxic Aquatic Systems Group, Institute of Microbiology, Department of Environment, Constructions and Design, University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Mendrisio, Switzerland.
Antoine Buetti-DinhAnoxic Aquatic Systems Group, Institute of Microbiology, Department of Environment, Constructions and Design, University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Mendrisio, Switzerland.
Samuele RomanAnoxic Aquatic Systems Group, Institute of Microbiology, Department of Environment, Constructions and Design, University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Mendrisio, Switzerland.
Tommaso FavaAnoxic Aquatic Systems Group, Institute of Microbiology, Department of Environment, Constructions and Design, University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Mendrisio, Switzerland.
Daniele PaganiniAnoxic Aquatic Systems Group, Institute of Microbiology, Department of Environment, Constructions and Design, University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Mendrisio, Switzerland.
Nicola StorelliAnoxic Aquatic Systems Group, Institute of Microbiology, Department of Environment, Constructions and Design, University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Mendrisio, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Lake Cadagno is a meromictic lake characterized by a stable euxinic chemocline that hosts a diverse community of anoxygenic phototrophic sulfur bacteria, among the earliest photosynthetic organisms on Earth. These microorganisms are key to understanding the evolution of photosynthesis; however, due to the rarity of permanently anoxic environments, their genetic and ecophysiological traits remain poorly characterized. Methods: We generated four high-quality genomes (>93% completeness, < 2% contamination), including two purple sulfur bacteria (PSB; Results: Nitrogen fixation (nif) genes were significantly upregulated in the chemocline, particularly in September, indicating a potential link between nitrogen fixation and bioconvection. Comparative genomic analyses revealed a higher abundance and diversity of nif genes in PSBs than in GSBs. Laboratory experiments demonstrated that PSBs ( Discussion: Collectively, genomic, transcriptomic, and experimental evidence confirms active nitrogen fixation in dominant phototrophic sulfur bacteria of Lake Cadagno. The upregulation of nif genes and their association with bioconvection suggest a functional coupling between nitrogen cycling and physical mixing processes, potentially mediated by

Indexed as

euxinic bottom zonegenomesmeromictic Lake Cadagnomodern analogsnitrogen fixationphototrophic sulfur bacteria

Identifiers

PMID42052384
PMCPMC13116554

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.