Evidence map›Paper›PMID 42052382›Full record

ArticleFrontiers in aging neuroscience2026

Sex-specific gray matter underpinnings of anxiety and their mediating mechanisms in

Guixiang He, Xiaofang Huang, Yi Xing, Lingling Yang, Haicun Shi, Haihua Sun, Weiguo Liu, Yuanzhang Zhou, Pinglei Pan

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In one paragraph

Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guixiang He *Department of Neurology, Affiliated Hospital 6 of Nantong University, Yancheng Third People's Hospital, Yancheng, China.
Xiaofang Huang *Department of Neurology, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, China.
Yi XingDepartment of Neurology, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, China.
Lingling YangDepartment of Neurology, Affiliated Hospital 6 of Nantong University, Yancheng Third People's Hospital, Yancheng, China.
Haicun ShiDepartment of Neurology, Affiliated Hospital 6 of Nantong University, Yancheng Third People's Hospital, Yancheng, China.
Haihua SunDepartment of Neurology, Affiliated Hospital 6 of Nantong University, Yancheng Third People's Hospital, Yancheng, China.
Weiguo LiuDepartment of Neurology, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, China.
Yuanzhang ZhouDepartment of Immunology, School of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Pinglei PanDepartment of Neurology, Affiliated Hospital 6 of Nantong University, Yancheng Third People's Hospital, Yancheng, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Anxiety is a prevalent non-motor symptom in Parkinson's disease (PD) with observed sex differences. This study aimed to investigate sex-specific gray matter volume (GMV) associations with anxiety and preliminarily explore the potential mediating role of these regional GMV alterations in the relationship between depressive and anxiety symptoms in Methods: A total of 108 Results: Whole-brain analysis revealed a significant sex-by-anxiety interaction in the right precuneus ( Conclusion: This study identified sex-specific GMV correlates of anxiety in

Indexed as

anxietyde novomediation analysesParkinson’s diseasesex differencesvoxel-based morphometry

Identifiers

PMID42052382
PMCPMC13111233

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.