ReviewFrontiers in surgery2026
Research hotspots and prospects on the correlation between subchondral bone and stem cells: bibliometrics and visual analysis.
Review in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: While the repair and regeneration of cartilage injuries remain a significant research challenge, the relationship between subchondral bone and stem cells has emerged as a new focus. However, a bibliometric analysis of the research trends in this specific area is currently lacking. Methods: We searched Web of Science Core Collection (WOSCC), Scopus, and PubMed for all relevant literature on the subchondral bone-stem cell relationship from database inception to September 3, 2025. CiteSpace was used to visualize annual publication counts, authors, institutions, countries, co-citations (authors, journals, references), and keywords. Results: A total of 1,267 publications were included. Research on the subchondral bone-stem cell relationship is an emerging focus. The most prolific author was Zhang Wei from China (15 publications). The institution with the most publications was the Chinese Academy of Sciences (52 publications), which also had the highest centrality (0.19). The most highly-cited author was ZHEN GH. AM J Sport Med was the most highly-cited journal and had the highest centrality (0.31). Keyword analysis showed "mesenchymal stem cells" as the most frequent term, while "cartilage" had the highest keyword centrality (0.27). The top 10 largest keyword clusters were #0 monosodium iodoacetate, #1 chitosan, #2 osteochondral defects, #3 scatter factor, #4 silk fibroin, #5 tissue engineering, #6 edetic acid, #7 microgels, #8 knee, and #9 cartilage repair, which were emerging research fronts. Conclusion: Research on the subchondral bone-stem cell relationship is an emerging focus. Consistent hotspots include cartilage and bone repair, cell therapy and tissue engineering, animal models and experiments, as well as transplantation and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.