Evidence map›Paper›PMID 42052348›Full record

ArticleFrontiers in veterinary science2026

Genotoxic exposures to volatile organic compounds in golden retrievers with and without multicentric lymphoma.

Ashleigh N Tindle, Lauren M Krueger, Brenna Swafford, Julia Labadie, Lauren A Trepanier

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ashleigh N TindleDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, WI, United States.
Lauren M KruegerDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, WI, United States.
Brenna SwaffordScientific Programs Department, Morris Animal Foundation, Denver, CO, United States.
Julia LabadieScientific Programs Department, Morris Animal Foundation, Denver, CO, United States.
Lauren A TrepanierDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, WI, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine multicentric lymphoma is a common cancer in dogs with poor long-term outcomes. In people, non-Hodgkin lymphoma is associated with volatile organic compounds (VOCs), but this risk is not clear for lymphoma in dogs. The objective of this study was to investigate whether dogs with lymphoma were more likely to be exposed to DNA-damaging concentrations of VOCs compared to unaffected controls. We measured stable urinary metabolites of the VOCs benzene, xylene, and 1,3-butadiene in golden retrievers with multicentric lymphoma and matched unaffected controls at 2 time points: the time of diagnosis and 1 year prior. We then determined genotoxic effects for xylene and bioactivated benzene in canine peripheral blood mononuclear cells (PBMCs)

Indexed as

cancer riskcaninegenotoxicitylymphomavolatile organic compounds (VOCs)

Identifiers

PMID42052348
PMCPMC13111026

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.