ArticleFrontiers in veterinary science2026
Metabolomic insights into thiamine-mediated metabolism in treating subclinical ketosis in dairy cows.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Subclinical ketosis (SCK) is a common condition in dairy cows, primarily caused by the excessive accumulation of Methods: To verify the purpose of the study, 60 SCK dairy cows with comparable body weight, milk yield, and lactation days were selected from a total of 1,126 dairy cows reared in the same environment. The selection was based on the criterion of blood beta-hydroxybutyrate concentration being greater than 1.2 mmol/L. Another 12 healthy dairy cows with similar productive performances were enrolled in the control treatment. Milk yield, milk quality, rumen fermentable parameters, rumen and blood metabolomics were measured to investigate the alleviative effects of thiamine on SCK. Results and discussion: The results showed that thiamine significantly decreased plasma BHBA concentrations, milk colony-forming units (CFU), and somatic cell counts, while significantly increasing milk yield, milk fat content, acetate levels, and the acetate-to-propionate (A/P) ratio compared to SCK cows (
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