Evidence map›Paper›PMID 42052234›Full record

ArticleResearch square2026

AI-driven credibility profiling of real-world patient experiences suggests overlooked kidney stone therapies warrant further investigation.

Alfredo Parra-Hinojosa, Andrés Gómez-Emilsson, Daniel C Elton

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alfredo Parra-HinojosaQualia Research Institute, Sacramento, CA, USA.ORCID 0000-0002-5096-0021
Andrés Gómez-EmilssonQualia Research Institute, Sacramento, CA, USA.
Daniel C EltonNational Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-0249-1387

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thousands of patients share their testimonials of kidney stone treatment efficacy online routinely, often with the hope of helping other patients understand what may help alleviate the severe suffering inflicted by the condition. Such testimonials generate vast data with potential hypothesis-generating insights that remain largely untapped. For this study, 4,899 publicly available online testimonials of nine different kidney stone products were collected across three different platforms: WebMD, Amazon, and Reddit. Using a state-of-the-art Large Language Model, these subjective reports were classified along multiple dimensions, focusing on reported effectiveness and rate of adverse effects. A methodology to minimize biases and extract statistically significant data from online testimonials is presented. Odds ratios and p-values were calculated using

Indexed as

Cost-Benefit AnalysisKidney CalculiKidney stonesNephrolithiasisnephrologyPatient Outcome AssessmentPhyllanhus NiruriProphylaxisurolithiasis

Identifiers

PMID42052234
PMCPMC13119306

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.