Evidence map›Paper›PMID 42052108›Full record

ArticleFrontiers in chemistry2026

Phytochemical profiling and multi-target pharmacological evaluation of

Mohammed Hassan, Islam Mostafa, Ahmed M Saad, Ahmed S AbdelKhalek, Mahmoud M Elaasser, Zepeng Yin, Mahmoud Sitohy, Mohamed El-Sadek, Omer I Fantoukh, Assem M El-Shazly and 1 more

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Plants (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohammed HassanDepartment of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Islam MostafaDepartment of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Ahmed M SaadBiochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.
Ahmed S AbdelKhalekDepartment of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Mahmoud M ElaasserRegional Center for Mycology and Biotechnology, Al-Azhar University, Cairo, Egypt.
Zepeng YinKey Laboratory of Fruit Postharvest Biology of Liaoning Province, Shenyang, China.
Mahmoud SitohyBiochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.
Mohamed El-SadekDepartment of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Omer I FantoukhDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Assem M El-ShazlyDepartment of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Mona FekryDepartment of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aimed to thoroughly profile the phytochemicals and pharmacological properties of Method: Chromatographic purification, LC/MS, total flavonoids, total phenolics, molecular docking and different pharmacological activity were used in this study to identify qualitatively and qualitatively the active compounds in extract and its activities. Results: Chromatographic purification of the petroleum ether and ethyl acetate fractions led to the isolation of four compounds: 3α- Friedelinol, Spinasterol, Dioctyl phthalate, and Kaempferol-3,7- diglucopyranoside. Additionally, the LC/MS profile of the hydro-alcoholic extract identified 35 metabolites, indicating a diverse chemical profile rich in fatty acids, phenolic propanoids, and terpenoids. Quantitative assays confirmed the extracts abundance in phenolics (65.9 ± 3.6 mg GAE/g extract) and flavonoids (25.8 ± 1.1 mg QE/g extract), correlating with notable in vitro antioxidant activity, as shown by low SC Discussion: These findings collectively support

Indexed as

antidiabeticanti-inflammatoryantioxidantasteraceaecytotoxicityLC-MS/MSSymphyotrichum squamatum

Identifiers

PMID42052108
PMCPMC13111398

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.