ArticleFrontiers in psychology2026
Exploring the temporal dynamics of circadian rhythm-aligned VR intervention in mitigating fear of cancer recurrence: mediating roles of illness uncertainty and hope in gynecological cancer patients.
Article in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Fear of cancer recurrence (FCR) is a prevalent and clinically significant psychological burden that adversely affects the quality of life and treatment adherence among gynecological cancer survivors. Virtual reality (VR), an emerging therapeutic modality, has demonstrated potential applications in oncology-related psychological interventions. This study investigates the efficacy of a chronotype-based timed VR intervention in alleviating FCR and explores the mediating mechanism of illness uncertainty (IU) and hope. Methods: A total of 63 patients were randomly allocated to either the VR intervention group ( Results: Baseline characteristics were well balanced (all Conclusion: A chronotype-based timed virtual reality intervention effectively reduces fear of cancer recurrence in gynecological cancer patients and acts through mediating pathways by reducing illness uncertainty and enhancing the level of hope. These findings provide empirical support for integrating chronotype-aligned virtual reality intervention into clinical practice and underscore the importance of considering temporal dynamics in psychological intervention design.
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