ArticleFrontiers in public health2026
Quantifying the exposure-response relationship between temperature exposure and semen quality.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: High temperature exposure impacts semen quality, but the exposure-response relationship needs further study. Objectives: Quantify the correlations and nonlinear relationships between apparent temperature (AT) exposure and semen quality parameters. Methods: A total of 5,114 individuals were enlisted as participants from a reproductive medicine center in Wenzhou, a developed coastal cities in eastern China. Multivariate linear regression models were used to quantify the correlations between AT exposure and semen quality parameters. Restricted cubic spline (RCS) and piecewise regression were employed to validate the nonlinear and threshold effects of the exposure-response relationships. Results: Each 1 °C rise in AT corresponded to considerable declines in progressive motility (-2.1165; 95% CI: -2.6219, -1.6111) and total motility (-4.8823; 95% CI: -6.2494, -3.5151). AT negatively influenced sperm motility during lag periods of 15-69 and 70-90 days ( Conclusions: Elevated exposure to apparent temperature in the 90 days prior to donation was associated with reduced semen quality. Avoiding excessive temperature exposure, particularly within a 2-week pre-ejaculation window, helps to maintain ideal semen quality.
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