The influence of simulated microgravity on MG-63 osteoblast-like cells cultured on polymeric scaffold.

Barbara Szaflarska, Kamila Walczak, Marcin Czepiel, Agata Kołodziejczyk, Elżbieta Pamuła

Abstract read

In one paragraph

Article in Biomaterials and biosystems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Barbara SzaflarskaAGH University of Kraków, Faculty of Space Technologies, al. Mickiewicza 30, 30-059 Kraków, Poland.

Kamila WalczakAGH University of Kraków, Faculty of Materials Science and Ceramics, al. Mickiewicza 30, 30-059 Kraków, Poland.

Marcin CzepielJagiellonian University Medical College, Institute of Pediatrics, Department of Clinical Immunology, ul. Wielicka 265, 30-663 Kraków, Poland.

Agata KołodziejczykAGH University of Kraków, Faculty of Space Technologies, al. Mickiewicza 30, 30-059 Kraków, Poland.

Elżbieta PamułaAGH University of Kraków, Faculty of Materials Science and Ceramics, al. Mickiewicza 30, 30-059 Kraków, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone degeneration remains a significant concern for long-term space missions due to microgravity-induced reductions in bone density and imbalances in bone remodeling processes. Discrepancies between spaceflight and ground-based analog studies complicate our understanding of the problem, particularly given the limitations of in vitro models that lack tissue-like environments. Research on osteoblast differentiation -crucial for bone maintenance - has yielded conflicting results, depending on the model and culture conditions. This study aims to establish a simple, scaffold-based bone tissue model using MG-63 cells cultured on poly(L-lactide-

Indexed as

Bone tissueMicrogravityPlgaPolymeric scaffoldsTissue engineering

Identifiers

PMID42051925

DOI10.1016/j.bbiosy.2026.100137

PMCPMC13112262

What OpenQuestion holds

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LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.