Evidence map›Paper›PMID 42051876›Full record

ReviewFrontiers in radiology2026

Coronary artery calcium scoring in 2026: strengths, limitations, and optimized clinical use.

Pierre Sabouret, Domenico Mario Giamundo, Julien Rosencher, Stefano Figliozzi

Abstract readReview
In one paragraph

Review in Frontiers in radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pierre SabouretHeart Institute and Action Group, Pitié-Salpétrière, Sorbonne University, Paris, France.
Domenico Mario GiamundoDepartment of Cardiology, Policlinico Casilino, Rome, Italy.
Julien RosencherDepartment of Cardiology, CMC Ambroise Paré, Neuilly-sur-Seine, France.
Stefano FigliozziCardio Center, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery calcium (CAC) scoring on non-contrast ECG-gated CT remains a robust, reproducible marker of total coronary atherosclerotic burden with clear prognostic value and consistent risk reclassification beyond contemporary clinical calculators. Recent studies (2018-2026) reinforce the 'power of zero' for near-term risk de-escalation, identify very high CAC (≥1,000) as a distinct, very-high-risk phenotype, and, importantly, provide randomized evidence that CAC-guided treatment reduces plaque progression. Advances in artificial intelligence (AI), spectral CT, and standardized reporting (SCCT/STR; CAC-DRS) expand opportunities for automated and incidental CAC detection. This mini-review summarizes updated strengths, limitations, and practice guidance; synthesizes new evidence (2024-2026); and includes a practical clinical decision flowchart for the selective use of CAC in prevention pathways.

Indexed as

atherosclerotic burdencardiovascular risk stratificationcoronary artery calcium (CAC) scorecoronary CT imagingprimary prevention

Identifiers

PMID42051876
PMCPMC13111553

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.