Evidence map›Paper›PMID 42051777›Full record

ReviewFrontiers in neurology

Advances in the diagnosis and management of post-stroke limb spasticity: a narrative review.

Menghan Su, Mingqing Yu, Ping Xu, Yong Fei

Abstract readReview
In one paragraph

Review in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Menghan SuZhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Mingqing YuZhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Ping XuZhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Yong FeiDepartment of Anesthesiology and Pain, The Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This review aims to provide a comprehensive overview of the current understanding and clinical management of post-stroke limb spasticity. Methods: Literature searches were conducted in PubMed and CNKI databases for articles published between January 2000 and June 2025, using keywords related to post-stroke spasticity, assessment, and interventions (botulinum toxin, rehabilitation, neuromodulation, surgery). The search was restricted to English-language articles addressing post-stroke limb spasticity. After screening, 68 studies were included and categorized by research theme. Results: Several interventions were identified as effective in alleviating post-stroke limb spasticity. Specifically, botulinum toxin injection has emerged as the primary choice for managing focal spasticity. Neuromodulation methods, including transcranial magnetic stimulation, transcranial direct current stimulation, spinal cord stimulation, and vagus nerve stimulation, demonstrated significant therapeutic potential. Conclusion: Neuromodulation techniques exert their effects by adjusting corticospinal tract excitability and promoting neural plasticity. However, additional randomized controlled trials are necessary to optimize stimulation settings and confirm their long-term effectiveness.

Indexed as

botulinum toxinlimb spasticityneuromodulationpost-stroke sequelaerehabilitation

Identifiers

PMID42051777
PMCPMC13110944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.