ReviewJournal of pain research2026
Efficacy of Cognitive Behavioral Therapy Combined with Exercise in Patients with Chronic Pain: A Systematic Review and Meta-Analysis.
Review in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Combined Internet-Based Cognitive Behavioral Therapy and Face-to-Face Physiotherapy in Primary Health Care for Chronic Widespread Pain: Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Central Sensitization and Pain Catastrophizing Are More Strongly Associated with Health-Related Quality of Life than Bioelectrical Impedance Analysis-Derived Body-Composition Measures in Patients with Chronic Low Back Pain.Diagnostics (Basel, Switzerland) · 2026Article
- Efficacy of Cognitive Behavioral Therapy Combined with Exercise in Patients with Chronic Pain: A Systematic Review and Meta-Analysis [Letter].Journal of pain research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To evaluate the effects of cognitive behavioral therapy (CBT) combined with exercise on multidimensional outcomes in adults with chronic pain, and to examine whether these effects were sustained at 3-, 6-, and 12-month follow-up. Patients and methods: PubMed, Embase, Web of Science, the Cochrane Library, and PsycINFO were searched from inception to December 30, 2025. Randomized controlled trials (RCTs) comparing CBT combined with exercise versus usual care or other control interventions were included. Results: Thirteen RCTs involving 1679 participants were included. Compared with controls, CBT combined with exercise produced small-to-moderate improvements in pain intensity and functional disability, although heterogeneity was observed across studies. Specifically, significant improvements were observed in pain intensity (SMD = -0.44, 95% CI: [-0.72, -0.16], Conclusion: CBT combined with exercise is a feasible multidisciplinary strategy for adults with chronic pain, yielding small-to-moderate improvements in pain intensity and functional disability, with benefits maintained at 3- and 6-month follow-up. Cognitive-behavioral outcomes, mental health, and quality of life also improved, but their long-term maintenance was limited. No significant benefits were observed in physical performance. Future research requires standardized CBT-exercise protocols and broader population representation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.