Evidence map›Paper›PMID 42051573›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Bridging Genetics and Precision Medicine in Parkinson's Disease through GP2.

Kajsa Atterling Brolin, Lara M Lange, Emily Navarro-Jones, Simona Jasaityte, Yuan Ye Beh, Zih-Hua Fang, Hirotaka Iwaki, Lietsel Jones, Christine Klein, Teresa Kleinz and 13 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Kajsa Atterling BrolinTranslational Neurogenetics Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden.ORCID 0000-0003-4832-922X
Lara M LangeLaboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.ORCID 0000-0002-7162-9821
Emily Navarro-JonesUCL Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, UK.ORCID 0009-0006-0353-8545
Simona JasaityteDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.ORCID 0009-0009-6030-2901
Yuan Ye BehDepartment of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Zih-Hua FangGerman Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany.ORCID 0000-0002-0225-8772
Hirotaka IwakiLaboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.ORCID 0000-0002-8982-7885
Lietsel JonesLaboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.ORCID 0000-0001-5293-0654
Christine KleinInstitute of Neurogenetics, University of Luebeck, Luebeck, Germany.ORCID 0000-0003-2102-3431
Teresa KleinzInstitute of Neurogenetics, University of Luebeck, Luebeck, Germany.ORCID 0009-0000-6313-7395
Hampton L LeonardLaboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.ORCID 0000-0003-2390-8110
Ignacio F MataGenome Sciences and Systems Biology, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0003-1198-0633
Alastair J NoyceCentre for Preventive Neurology, Wolfson Institute of Population Health, Queen Mary University of London, UK.
Njideka OkubadejoNeurology Unit, Department of Medicine, College of Medicine, University of Lagos, Nigeria.ORCID 0000-0003-2975-8803
Paula Saffie AwadClinica Santa Maria, Santiago, Chile.ORCID 0000-0002-8056-365X
Laurel ScrevenGlobal Parkinson's Genetics Program (GP2), Chevy Chase, MD, USA.ORCID 0000-0002-1330-7779
Ai Huey TanDepartment of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0002-2979-3839
Marco ToffoliDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.ORCID 0000-0002-3255-9648
Dan VitaleLaboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.ORCID 0000-0002-0637-3671
Andrew SingletonGlobal Parkinson's Genetics Program (GP2), Chevy Chase, MD, USA.ORCID 0000-0001-5606-700X
Cornelis BlauwendraatGlobal Parkinson's Genetics Program (GP2), Chevy Chase, MD, USA.ORCID 0000-0001-9358-8111
Mike NallsLaboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.
Huw R MorrisUCL Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, UK.ORCID 0000-0002-5473-3774

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the Global Parkinson's Genetics Program (GP2) we aim to advance precision medicine by integrating large-scale clinico-genetic data from diverse populations worldwide. We investigated potentially trial-eligible carriers of pathogenic and high-risk

Identifiers

PMID42051573
PMCPMC13119358

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.