ArticleFrontiers in cardiovascular medicine2026
Case Report: Transcatheter closure of paravalvular leak following left ventricular assist device and aortic valve replacement.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: End-stage dilated cardiomyopathy (DCM) is a common cause of end-stage heart failure, and some patients may eventually require heart transplantation. Such patients often need a left ventricular assist device (LVAD) as a bridge to heart transplantation, and those with severe aortic regurgitation may undergo concurrent aortic valve replacement. Paravalvular leak (PVL) is a complication following valve surgery that can lead to worsening heart failure; however, reports on transcatheter closure of PVL after LVAD implantation are rare. Case summary: This article reports the case of a 39-year-old male patient with DCM who underwent CorHeart 6 LVAD implantation, aortic bioprosthetic valve replacement, and tricuspid valvuloplasty due to end-stage heart failure. A follow-up echocardiogram 2 months post-surgery revealed a progressively worsening paravalvular leak around the aortic bioprosthetic valve (maximum regurgitant jet width 3.4 mm, regurgitant jet area 20.5 cm Conclusion: This case suggests that transcatheter closure may be a safe and effective treatment option for high-risk patients who develop PVL following LVAD implantation combined with aortic valve replacement, providing a reference for the individualized management of similar complex cases.
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