Evidence map›Paper›PMID 42051342›Full record

ArticleFrontiers in nutrition2026

Plant-based caloric restriction diets versus conventional calorie-restricted diets for weight loss and metabolic health in obese adults: a 12-week randomized, open-label, non-inferiority trial.

Kelibinuer Mutailipu, Liu Yang, Yaling Fang, Shihui Lei, Junwei Guo, Hang Yuan, Shuwei Liu, Yue Chen, Cuiling Zhu, Shen Qu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kelibinuer MutailipuDepartments of Obesity and Metabolic Syndrome, Endocrinology & Metabolism, and Obesity Diagnosis and Treatment Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Liu YangDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Yaling FangDepartments of Obesity and Metabolic Syndrome, Endocrinology & Metabolism, and Obesity Diagnosis and Treatment Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Shihui LeiDepartments of Obesity and Metabolic Syndrome, Endocrinology & Metabolism, and Obesity Diagnosis and Treatment Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Junwei GuoDepartments of Obesity and Metabolic Syndrome, Endocrinology & Metabolism, and Obesity Diagnosis and Treatment Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Hang YuanDepartments of Obesity and Metabolic Syndrome, Endocrinology & Metabolism, and Obesity Diagnosis and Treatment Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Shuwei LiuDepartments of Obesity and Metabolic Syndrome, Endocrinology & Metabolism, and Obesity Diagnosis and Treatment Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yue ChenDepartments of Obesity and Metabolic Syndrome, Endocrinology & Metabolism, and Obesity Diagnosis and Treatment Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Cuiling ZhuDepartments of Obesity and Metabolic Syndrome, Endocrinology & Metabolism, and Obesity Diagnosis and Treatment Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Shen QuDepartments of Obesity and Metabolic Syndrome, Endocrinology & Metabolism, and Obesity Diagnosis and Treatment Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Falin ZhaoSchool of Public Administration, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Le BuDepartments of Obesity and Metabolic Syndrome, Endocrinology & Metabolism, and Obesity Diagnosis and Treatment Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Plant-based caloric restriction diet (PB-CRD), combining plant-based nutrition with intermittent caloric restriction, represent a structured dietary strategy to obesity management. This study compared the effects of PB-CRD and calorie-restricted diet (CRD) on weight loss, and metabolic health, hypothesizing that PB-CRD is non-inferior to CRD for weight loss. Methods: In this 12-week, open-label, non-inferiority trial, 80 participants with obesity (body mass index [BMI]: 28-40 kg/m Results: Of the 80 participants (mean BMI: 32.03 ± 3.46 kg/m Conclusion: Both PB-CRD and CRD were effective for weight loss, with PB-CRD demonstrating non-inferiority. Furthermore, PB-CRD offered superior benefits in reducing total body fat and improving uric acid metabolism, while improving insulin sensitivity and liver function in adults with obesity. Clinical trial registration: Identifier ChiCTR1800015156.

Indexed as

calorie-restricted dietmetabolic healthobesityplant-based dietweight loss

Identifiers

PMID42051342
PMCPMC13111110

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.