Evidence map›Paper›PMID 42051294›Full record

ArticlebioRxiv : the preprint server for biology2026

Mechanism of phospholipid transport to the bacterial outer membrane by TAM.

Alanah G Eisenhuth, Lachlan S R Adamson, Catherine Zhang, Ghaeath S K Abbas, Rachel A North, Denisse L Leyton, Harris D Bernstein, Simon H J Brown, Alastair G Stewart, Constance B Bailey and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alanah G EisenhuthCentre for Drug Discovery Innovation, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-4313-5680
Lachlan S R AdamsonCentre for Drug Discovery Innovation, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-9862-9557
Catherine ZhangSchool of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.ORCID 0009-0005-4834-0674
Ghaeath S K AbbasCentre for Drug Discovery Innovation, The University of Sydney, Sydney, NSW, Australia.
Rachel A NorthCentre for Drug Discovery Innovation, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0001-5011-1567
Denisse L LeytonResearch School of Biology, Australian National University, Canberra, ACT, Australia.ORCID 0000-0003-4808-9289
Harris D BernsteinGenetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases / National Institutes of Health, Bethesda, MD, USA.
Simon H J BrownSchool of Science, Molecular Horizons, and the Australian Research Council Centre for Cryo-electron Microscopy of Membrane Proteins, University of Wollongong, Wollongong, NSW, Australia.
Alastair G StewartMolecular, Structural and Computational Biology Division, The Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia.ORCID 0000-0002-2070-6030
Constance B BaileyCentre for Drug Discovery Innovation, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-4668-7245
Anthony S DonCentre for Drug Discovery Innovation, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0003-1655-1184
Aidan B GrosasSchool of Science, Molecular Horizons, and the Australian Research Council Centre for Cryo-electron Microscopy of Membrane Proteins, University of Wollongong, Wollongong, NSW, Australia.ORCID 0009-0008-5685-8619
Matthew Thomas DoyleCentre for Drug Discovery Innovation, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-1876-1209

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gram-negative bacteria transport phospholipids from the inner membrane (IM) to the outer membrane (OM) via poorly understood processes. These processes are essential for cell growth and the establishment of an antibiotic-resistant barrier. Here, we conducted single-particle cryo-electron microscopy,

Identifiers

PMID42051294
PMCPMC13119328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.