Evidence map›Paper›PMID 42051064›Full record

ArticleRenal failure2026

Impact of combined ECMO - CRRT support on patient outcomes and risk factors: a multicenter retrospective study.

Xin Wang, Yueguo Wang, Pengfei Ren, Yuan Yuan, Jie Wang, Xiancong Wang, Yulan Wang, Jian Sun, Huanli Wang, Jie Qin and 5 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xin WangGraduate School, Bengbu Medical University, Bengbu, China.
Yueguo WangDepartment of Emergency Medicine, the First Affiliated Hospital of the University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Pengfei RenGraduate School, Bengbu Medical University, Bengbu, China.
Yuan YuanDepartment of Intensive Care Unit, the First Hospital of Jiaxing, Affiliated Hospital of Jiaxing University, Jiaxing, China.
Jie WangGraduate School, Bengbu Medical University, Bengbu, China.
Xiancong WangDepartment of Emergency Medicine, the First Affiliated Hospital of the University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Yulan WangDepartment of Emergency Medicine, the First Affiliated Hospital of the University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Jian SunDepartment of Emergency Medicine, the First Affiliated Hospital of the University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Huanli WangDepartment of Emergency Medicine, the First Affiliated Hospital of the University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Jie QinDepartment of Emergency Medicine, Taizhou People's Hospital, Taizhou, China.
Yan ShiDepartment of Emergency Medicine, Huai'an Second People's Hospital, Huai, China'an.
Haichen YangDepartment of Emergency Medicine, Huai'an Second People's Hospital, Huai, China'an.
Shusheng ZhouDepartment of Emergency Medicine, the First Affiliated Hospital of the University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Jun XuDepartment of Emergency Medicine, Peking Union Medical College Hospital, Beijing, China.
Kui JinGraduate School, Bengbu Medical University, Bengbu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the association of continuous renal replacement therapy (CRRT) use with the prognosis of patients undergoing extracorporeal membrane oxygenation (ECMO) and to explore its relationship with changes in blood cell components.

methodsData from four tertiary hospitals in China were retrospectively reviewed for patients who received ECMO support between September 2019 and June 2024. Univariable and multivariable logistic and Cox regression analyses were used to identify factors associated with in-hospital mortality. As an exploratory analysis, peripheral blood cell counts over the first 4 days after ECMO initiation were compared between groups, with hemoglobin and platelet values adjusted for transfusions.

resultsAmong 158 ECMO patients, 89 received CRRT and 69 did not, with an overall in-hospital mortality of 41.1%. Mortality was higher in the CRRT+ group than in the CRRT - group (53.9% vs. 24.6%,

conclusionsCRRT use was linked to poorer prognosis in ECMO patients, including higher in-hospital mortality, and was associated with marked changes in blood cell components.

Indexed as

Acute Kidney InjuryContinuous Renal Replacement TherapyExtracorporeal Membrane OxygenationAdultChinaFemaleHospital MortalityHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk Factorsblood cell componentsContinuous renal replacement therapyextracorporeal membrane oxygenationmortalityrisk factors

Identifiers

PMID42051064
PMCPMC13130235

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.