Evidence map›Paper›PMID 42050628›Full record

ArticleBMC medical education2026

The impact of interactive digital tools on genetics education: a field study across large and small learning groups.

Eva Barrio, Estela Solanas, Clara Alcaine, Sonia Emperador, Jacobo Ayensa-Jimenez, Andrés Mena, Jesús Ciriza

Abstract read
In one paragraph

Article in BMC medical education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eva BarrioDepartment of Anatomy and Histology, University of Zaragoza, Zaragoza, 50009, Spain.
Estela SolanasDepartment of Anatomy and Histology, University of Zaragoza, Zaragoza, 50009, Spain.
Clara AlcaineTissue Microenvironment (TME) Lab, Aragon Institute for Engineering Research (I3A), University of Zaragoza, Campus Rio Ebro, Mariano Esquillor s/n, Edificio I+D+I, Zaragoza, 50018, Spain.
Sonia EmperadorDepartment of Anatomy and Histology, University of Zaragoza, Zaragoza, 50009, Spain.
Jacobo Ayensa-JimenezTissue Microenvironment (TME) Lab, Aragon Institute for Engineering Research (I3A), University of Zaragoza, Campus Rio Ebro, Mariano Esquillor s/n, Edificio I+D+I, Zaragoza, 50018, Spain.
Andrés MenaBiomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Zaragoza, 50018, Spain.
Jesús CirizaDepartment of Anatomy and Histology, University of Zaragoza, Zaragoza, 50009, Spain. jeciriza@unizar.es.

Funding

Universidad de Zaragoza PIIDUZ_1, Emergentes ID 5091
6 · The paper itself

Abstract

backgroundKaryotype analysis is a core component of medical genetics education, yet many students find it challenging, particularly in large classes where opportunities for individualized feedback are limited. Digital tools may help address these constraints, but evidence on their use across different class sizes remains limited. This study examined the use of an interactive digital tool to support learning in karyotype analysis within undergraduate medical education.

methodsThe study involved 252 first-year medical students who used an interactive digital tool integrated into the medical genetics curriculum and delivered asynchronously through the university's virtual learning platform. Students completed structured online activities requiring the construction and interpretation of karyograms from real metaphase images. Data were collected using pre- and post-activity surveys assessing self-reported knowledge, diagnostic confidence, and perceptions of learning. Descriptive statistics and comparative analyses were used to examine changes over time and to explore differences between small and large teaching cohorts.

resultsFollowing the intervention, students reported improved clarity of key genetic concepts and increased confidence in identifying chromosomal abnormalities compared with pre-activity measures. Most participants also perceived the tool as useful for supporting their learning and reported high levels of engagement with the activity. Similar patterns were observed in both small and large cohorts, suggesting that the digital tool functioned comparably across different class sizes.

conclusionsThe findings indicate that interactive digital tools can successfully support the acquisition of complex scientific domains, particularly in contexts characterized by large enrollments and limited access to laboratory-based instruction. Although conducted within medical genetics education, the study has broader relevance for higher education settings seeking scalable approaches to teaching conceptually demanding content. The results may inform educational policy and curriculum decisions related to the integration of digital resources in health professions education.

trial registrationNot applicable.

Indexed as

Computer-Assisted InstructionEducation, Medical, UndergraduateGenetics, MedicalKaryotypingCurriculumDigital MediaFemaleHumansMaleStudents, MedicalCytogeneticsDigital learning toolsEducational innovationKaryotype analysisMedical education

Identifiers

PMID42050628
PMCPMC13267712

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.