Evidence map›Paper›PMID 42050549›Full record

ArticleAlgorithms for molecular biology : AMB2026

Pattern matching with Elastic-Degenerate strings and Elastic-Founder graphs.

Rocco Ascone, Giulia Bernardini, Alessio Conte, Massimo Equi, Esteban Gabory, Roberto Grossi, Nadia Pisanti

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In one paragraph

Article in Algorithms for molecular biology : AMB, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Rocco AsconeUniversity of Trieste, Trieste , Italy.
Giulia BernardiniUniversity of Trieste, Trieste , Italy. giulia.bernardini@units.it.
Alessio ConteUniversity of Pisa, Pisa , Italy.
Massimo EquiUniversity of Helsinki, Helsinki , Finland.
Esteban GaboryCWI Amsterdam, Amsterdam, Netherlands.
Roberto GrossiUniversity of Pisa, Pisa , Italy.
Nadia PisantiUniversity of Pisa, Pisa , Italy. nadia.pisanti@unipi.it.

Funding

Gruppo Nazionale per il Calcolo Scientifico CUP_E53C24001950001Horizon 2020 Framework Programme 872539Horizon 2020 Framework Programme 956229Ministero dell'Università e della Ricerca MUR - FSE REACT EU - PON R\&I 2014-2020Ministero dell'Università e della Ricerca PRIN 2022 YRB97K PINCNextGenerationEU ECS00000017
6 · The paper itself

Abstract

Elastic Degenerate (ED) strings and Elastic Founder (EF) graphs, here collectively named variable strings, are two representations of acyclic components of pangenomes which extend the well-known notion of indeterminate string. Recent studies have focused extensively on algorithmic tasks involving these structures and other forms of variable strings that they generalize. Among such tasks, the basic operation of matching a pattern into a text, a fundamental toolkit for pangenomic data analysis, deserves special attention. In this paper, (1) we establish a clear taxonomy across ED strings and EF graphs, categorizing types of variable strings from the simplest linear (solid) string to the most complex general cases; (2) we consider the problem MATCH(X,Y) of matching a solid or variable pattern of type X into a variable text of type Y, and investigate its time complexity when X and Y are chosen from types of variable strings in the taxonomy of (1). For all possible X and Y, we either provide a non-trivial, often sub-quadratic, upper bound for MATCH(X,Y), or we prove a quadratic conditional lower bound, taking as a reference the existing quadratic conditional lower bounds for MATCH(SOLID,ED) and MATCH(SOLID,EF). A preliminary version of this work appeared in [Ascone et al., WABI 2024].

Indexed as

Degenerate stringFine-grained complexityFounder graphGenome variantPangenomicsPattern matching

Identifiers

PMID42050549
PMCPMC13182080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.