Evidence map›Paper›PMID 42050321›Full record

ArticleScientific reports2026

Stretch strain shifts optic nerve head astrocyte metabolism to enrich α-ketoglutarate and the pentose phosphate pathway.

Usa Suwannasual, Katherine R Smart, Olivia Young, Eul Hyun Suh, Teresa D Golden, Denise M Inman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Usa SuwannasualDepartment of Pharmaceutical Sciences, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, USA.
Katherine R SmartDepartment of Chemistry, University of North Texas, Denton, TX, USA.
Olivia YoungDepartment of Pharmaceutical Sciences, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, USA.
Eul Hyun SuhDepartment of Pharmaceutical Sciences, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, USA.
Teresa D GoldenDepartment of Chemistry, University of North Texas, Denton, TX, USA.
Denise M InmanDepartment of Pharmaceutical Sciences, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, USA. denise.inman@unthsc.edu.

Funding

Metabolic vulnerability as a disease target for glaucomaR01EY026662 · NEI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI DENISE M INMAN · 2016 to 2026
$4.1M
Optic nerve head metabolic change promotes fibrosisR21EY036552 · NEI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI INMAN, DENISE M · 2024 to 2025
$382k
NEI NIH HHS EY026662NEI NIH HHS R01 EY026662NEI NIH HHS R21 EY036552
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

FibrosisLamininMetabolic reprogrammingStable isotope tracingYAP

Identifiers

PMID42050321
PMCPMC13316025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.