Evidence map›Paper›PMID 42050218›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2026

Genome-wide association study of soybean germplasm derived from modern Canadian and Chinese soybean cultivars to identify novel genes conferring soybean cyst nematode resistance.

Scott Moore, Owen Wally, Albert Tenuta, Mohsen Yoosefzadeh Najafabadi, Christopher Grainger, Milad Eskandari, Istvan Rajcan

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Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Scott MooreDepartment of Plant Agriculture, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Owen WallyHarrow Research and Development Centre, Agriculture and Agri-Food Canada, 2585 County Road 20, Harrow, ON, N0R 1G0, Canada.
Albert TenutaOntario Ministry of Agriculture, Food and Agribusiness, University of Guelph, Ridgetown Campus, Agronomy Building, 120 Main Street East, Ridgetown, ON, N0P 2C0, Canada.
Mohsen Yoosefzadeh NajafabadiDepartment of Plant Agriculture, University of Guelph, Guelph, ON, N1G 2W1, Canada.ORCID http://orcid.org/0000-0003-3631-4493
Christopher GraingerDepartment of Plant Agriculture, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Milad EskandariDepartment of Plant Agriculture, University of Guelph, Guelph, ON, N1G 2W1, Canada.ORCID http://orcid.org/0000-0003-0862-4048
Istvan RajcanDepartment of Plant Agriculture, University of Guelph, Guelph, ON, N1G 2W1, Canada. irajcan@uoguelph.ca.ORCID http://orcid.org/0000-0001-5156-2482

Funding

Agriculture and Agri-Food Canada CFCRA Soybean Cluster - Activity 7Grain Farmers of Ontario CFCRA Soybean Cluster - Activity 7National Science and Engineering Research Council of Canada (NSERC) ALLRP 590802 - 23SeCan CFCRA Soybean Cluster - Activity 7
6 · The paper itself

Abstract

key messageDeveloping genetically resistant soybean cultivars is key in controlling the most damaging soybean disease worldwide; soybean cyst nematode (SCN) is critical for soybean production. Development and spread of new HG types of SCN that break down current resistance genes warrant continuous efforts to identify novel resistance sources. Here, a GWAS study in a diversity panel consisting of modern Canadian and Chinese soybean cultivars was used to identify novel marker-trait associations in the soybean genome derived from Chinese germplasm. Soybean cyst nematode (SCN), caused by Heterodera glycines Ichinohe, is the most destructive pathogen affecting soybean production in North America. Overreliance on plant introduction (PI) 88788 as a resistance source in commercial soybean cultivars has led to SCN field populations shifting toward virulence against this resistance source. Modern Chinese soybean cultivars have emerged as potential sources of both known and novel SCN resistance genes. This study aimed to investigate the genetics underlying HG-type 2.5.7 SCN resistance in a genomic diversity panel (n = 201) comprised of modern Canadian (CD), Chinese (CH), and combined CD-CH soybean genotypes through a genome-wide association study (GWAS). Genotyping-by-sequencing (GBS) detected 15,932 single nucleotide polymorphisms (SNPs). Phenotypic SCN resistance was assessed by infesting genotypes in the GWAS panel using a greenhouse bioassay with HG-type 2.5.7 to calculate the female index (FI). FarmCPU detected one SNP on chromosome 9, explaining 7.26% of phenotypic variation in SCN resistance, while BLINK identified the same chromosome 9 SNP at 35.15% and two additional ones on chromosomes 8 and 13, explaining 24.81 and 15.92% variation, respectively. Alternative alleles for these SNPs were contributed by CH and CD-CH genotypes. Three candidate genes were identified in this study, in which Glyma.09g238800 appears to be the strongest, but verification is warranted in future research. The significant SNPs identified in this study show the genetic utility of modern Chinese soybean germplasm in developing soybean cultivars with alternative SCN resistance genes to enhance the sustainability of developing SCN-resistant soybean cultivars in North America.

Indexed as

Disease ResistanceGenes, PlantGlycine maxPlant DiseasesTylenchoideaAnimalsCanadaChromosome MappingGenetic MarkersGenome-Wide Association StudyGenotypePhenotypePolymorphism, Single NucleotideQuantitative Trait LociGenetic Markers

Identifiers

PMID42050218

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.