Evidence map›Paper›PMID 42050214›Full record

ArticleGeroScience2026

Greater recalled pain and movement-evoked pain are associated with longer 400-m walk and repeat stair climb timein older adults: the study of muscle, mobility, and aging.

Theresa Mau, Corey B Simon, Haley N Barnes, Megan Hetherington-Rauth, Scott R Bauer, Elsa S Strotmeyer, Nancy E Lane, Michael C Rowbotham, Ashley A Weaver, Terri L Blackwell and 7 more

Abstract read
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In one paragraph

Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Theresa MauCenter for Aging Science, Sutter Health Research Institute, San Francisco, CA, USA. theresa.mau@ucsf.edu.ORCID http://orcid.org/0000-0003-4278-6438
Corey B SimonDepartment of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Haley N BarnesCenter for Aging Science, Sutter Health Research Institute, San Francisco, CA, USA.
Megan Hetherington-RauthCenter for Aging Science, Sutter Health Research Institute, San Francisco, CA, USA.
Scott R BauerDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Elsa S StrotmeyerDepartment of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Nancy E LaneDepartment of Medicine and Rheumatology, University of California Davis, Sacramento, CA, USA.
Michael C RowbothamDepartment of Anesthesia, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Ashley A WeaverDepartment of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Terri L BlackwellCenter for Aging Science, Sutter Health Research Institute, San Francisco, CA, USA.
Yurun CaiDepartment of Health and Community Systems, University of Pittsburgh School of Nursing, Pittsburgh, PA, USA.
Nancy W GlynnDepartment of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Bret H GoodpasterAdventHealth, Translational Research Institute, Orlando, FL, USA.
Steven R CummingsCenter for Aging Science, Sutter Health Research Institute, San Francisco, CA, USA.
Anne B NewmanDepartment of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Peggy M CawthonCenter for Aging Science, Sutter Health Research Institute, San Francisco, CA, USA.
Stephen B KritchevskyDepartment of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Funding

Study of Muscle, Mobility and Aging: SOMMA2R01AG059416 · NIA · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI STEVEN RON CUMMINGS, Peggy Mannen Cawthon · 2018 to 2026
$70.3M
Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamie Nicole Justice · 2002 to 2026
$36.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
The Study of Muscle, Mobility and Aging with Knee OAR01AG070647 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Nancy E Lane · 2021 to 2026
$2.5M
Muscle Quantity, Quality, Function, and Biomarker Associations with Longitudinal Preservation of Bone Microarchitecture and Bone Strength in Older AdultsR01AR086541 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAULEY, JANE ANN, STROTMEYER, ELSA S. · 2025 to 2025
$1.6M
Bone microarchitecture and bone strength relationships to muscle quantity, quality and function in older adultsR01AR076752 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAULEY, JANE ANN, STROTMEYER, ELSA S. · 2019 to 2023
$1.5M
Stress Reactivity and Low Back Pain in Older Adults: Influences on Disability (ReLOAD)K76AG074943 · NIA · DUKE UNIVERSITY · PI Corey Simon · 2022 to 2026
$1.0M
NCATS NIH HHS UL1TR001420NIAMS NIH HHS R01 AR076752NIAMS NIH HHS R01 AR086541NIA NIH HHS 1K76AG074903NIA NIH HHS K76 AG074943NIA NIH HHS K76AG074943NIA NIH HHS P30AG021332NIA NIH HHS P30AG024827NIA NIH HHS R01AG059416NIA NIH HHS R01AG070647
6 · The paper itself

Abstract

Musculoskeletal pain and mobility disability are common in older adults, but relationships among pain parameters and physical performance are poorly understood. We quantified the impact of different pain measures-recalled and movement-evoked pain-on walk and stair climb time in older adults from the Study of Muscle, Mobility and Aging (SOMMA). In SOMMA (N = 879, age = 76.3 ± 5.0 years, 59% women, 84% non-Hispanic White), participants completed usual pace 400-m walk (avg = 6.6 ± 1.2 min) and stair climb tests (avg = 26.6 ± 7.2 s.). Assessments of recalled pain included the Brief Pain Inventory, total lower body pain, and Neuropathy Total Symptom Score. Movement-evoked pain was assessed separately for the 400-m walk and stair climb tasks. Multivariable linear regression modeled the associations of pain with time to complete the tasks, reported as β [95%CI] expressed per SD increment of pain measure or per pain categories, adjusted for age, sex, race/ethnicity, BMI, prescription medications, and depressive symptoms. A greater degree of any pain measure was associated with longer (worse) physical performance time. For each SD increment in lower body pain (back, hips, knees, feet/ankles), participants had longer walk (+ 10.5 s [6.1, 14.8]) and stair climb time (+ 0.6 s [0.1, 1.1]). Compared to participants with no pain, walk time was longer in those with resting pain (+ 22.8 s [4.9,40.6]) and movement-evoked pain (+ 19.1 s [8.9, 29.2]) but not movement-evoked hypoalgesia (+ 12.6 s [-4.4, 29.7]); stair climb showed similar patterns. Different pain assessments captured heterogeneous pain contextual factors (e.g., type, state, temporality) among these older adults. However, all pain measures were similarly associated with physical performance, suggesting that multiple assessments may provide a more comprehensive characterization of pain and physical function outcomes.

Indexed as

400-m walkMovement-evoked painPain contextual factorsRecalled painRepeat stair climb

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.