Evidence map›Paper›PMID 42050181›Full record

ArticleNature medicine2026

Clinical trials for continuously monitored and updated AI systems.

Wouter A C van Amsterdam, Michael Oberst, Jean Feng, Jenna Wiens, Shengpu Tang, Shalmali Joshi, Rajesh Ranganath, Mark Sendak, Uri Shalit, Julia E Vogt and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Wouter A C van Amsterdam *Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID http://orcid.org/0000-0002-3181-0810
Michael Oberst *Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-1720-6702
Jean Feng *University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-2041-3104
Jenna WiensUniversity of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-1057-7722
Shengpu TangEmory University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-4213-2015
Shalmali JoshiColumbia University, New York, NY, USA.
Rajesh RanganathNew York University, New York, NY, USA.ORCID http://orcid.org/0000-0003-2854-3376
Mark SendakVega Health, Durham, NC, USA.ORCID http://orcid.org/0000-0001-5828-4497
Uri ShalitTel Aviv University, Tel Aviv, Israel.
Julia E VogtETH Zurich, Zurich, Switzerland.
Brett Beaulieu-JonesUniversity of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-6700-1468
Muhammad MamdaniOntario Health, Toronto, Ontario, Canada.
David KentTufts University, Boston, MA, USA.
Patrick J HeagertyUniversity of Washington, Seattle, WA, USA.
Thomas R FlemingUniversity of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0420-5068
Anna GoldenbergUniversity of Toronto, Toronto, Ontario, Canada. anna.goldenberg@utoronto.ca.

Funding

Characterizing Population Differences between Clinical Trial and Real World PopulationsR00NS114850 · NINDS · UNIVERSITY OF CHICAGO · PI BEAULIEU-JONES, BRETT K · 2023 to 2025
$740k
AHRQ HHS R01 HS027431NINDS NIH HHS R00 NS114850U.S. Department of Health & Human Services | Agency for Healthcare Research and Quality (AHRQ) R01HS027431U.S. Department of Health & Human Services | National Institutes of Health (NIH) R37-AI29168
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42050181
PMCPMC13321079

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.