Evidence map›Paper›PMID 42050170›Full record

ArticleNPJ digital medicine2026

External validation of a machine learning model for delivery mode prediction after induction.

Iolanda Ferreira, Joana Simões, João Correia, Ana Luísa Areia

Abstract read
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iolanda FerreiraObstetrics Department, Unidade Local de Saúde Coimbra, Coimbra, Portugal. 10862@ulscoimbra.min-saude.pt.
Joana SimõesDepartment of Informatics Engineering, University of Coimbra, Centre for Informatics and Systems of the University of Coimbra, Coimbra, Portugal.
João CorreiaDepartment of Informatics Engineering, University of Coimbra, Centre for Informatics and Systems of the University of Coimbra, Coimbra, Portugal.
Ana Luísa AreiaObstetrics Department, Unidade Local de Saúde Coimbra, Coimbra, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

No machine learning (ML) models for predicting delivery mode after labor induction (IOL) have been externally validated. We aimed to develop and validate one using medical records. Portuguese tertiary center data (n = 2434) were used for development and internal validation, and Consortium on Safe Labor data (n = 10,591) for external validation. Outcomes are vaginal delivery (VD) or cesarean section (CS). Internal validation employed different ML approaches, aiming for model simplification. Logistic regression performed best on internal validation: AUROC:0.793; F1-score:0.748; PPV:0.752, with good calibration and decision curve analysis (DCA), being selected for simplification. Simplified top-13 features model was selected for external validation: AUROC:0.808; F1-score:0.781; PPV:0.822, tending for VD (99.6%) while avoiding false-positives (0.5%). Calibration curves underestimated CS risk by 10-75%; DCA showed good net benefit. The model's good AUROC and DCA suggest clinical utility. Calibration curve underestimation of CS risk may result from outcome imbalance between datasets.

Identifiers

PMID42050170
PMCPMC13333831

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.